Apoptosis

Apoptosis is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, DNA fragmentation, and mRNA decay.

Cat. No.	製品名	CAS No.	Purity
T6892	Niraparib tosylate	1038915-73-9	98%
T6892	MK-4827(Niraparib) tosylate (with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
T6893	MK-886	118414-82-7	98%
T6893	MK-886 is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.
T2577	Dienogest	65928-58-7	98%
T2577	Dienogest is an orally-active, semisynthetic, fourth generation, nonethinylated progestogen with antiproliferative, antiandrogenic, anti-inflammatory and antiang...
T4123	LYN-1604	2088939-99-3	98%
T4123	LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
T6712	Tyrphostin AG 879	148741-30-4	98%
T6712	Tyrphostin AG 879 effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.
T1144	Lidocaine hydrochloride	73-78-9	98%
T1144	Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmic agent. Its actions are more intense and its effects more prolonged...
T1890	Pracinostat	929016-96-6	98%
T1890	Pracinostat is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral dosing. Da...
T0607	Dihydroartemisinin	71939-50-9	98%
T0607	Dihydroartemisinin is a metabolite of artemisinin.
T0239	Lonidamine	50264-69-2	98%
T0239	Lonidamine is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK)....
T2A2481	Taurochenodeoxycholic Acid	516-35-8	98%
T2A2481	Taurochenodeoxycholic acid is one of the main bioactive substances of animals' bile acid.
T0440	Oxcarbazepine	28721-07-5	98%
T0440	Oxcarbazepine is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activit...
TN4675	Nortrachelogenin	34444-37-6	98%
TN4675	Nortrachelogenin ((-)-Wikstromol), which can be extracted from Partrinia scabiosaefolia, has antifungal activity and induces membrane disruption and cysteinyl as...
T2S1008	Oxysophoridine	54809-74-4	98%
T2S1008	Oxysophoridine has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective...
T14298	Rimiducid	195514-63-7	98%
T14298	Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affin...
T6629	PYR-41	418805-02-4	98%
T6629	PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.
T2322	Fimasartan	247257-48-3	98%
T2322	Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimas...
T4230	PF-3758309 hydrochloride	1279034-84-2	98%
T4230	PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potent...
T9150	SCR130	2377858-38-1	98%
T9150	1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo- is enzyme inhibition, antiproliferative effects and antifungal activity.
T5379	(Rac)-Antineoplaston A10	77658-84-5	98%
T5379	Antineoplaston A10 is a naturally occurring substance and the first antineoplaston in the human body to be chemically identified. It displayed anti-proliferative...
T4263	BAY 61-3606	732983-37-8	98%
T4263	BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effec...