| T4123 |
LYN-1604
|
2088939-99-3
|
98%
|
|
|
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
|
| T1934 |
Bay 11-7085
|
196309-76-9
|
98%
|
|
|
Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
|
| T2S1008 |
Oxysophoridine
|
54809-74-4
|
98%
|
|
|
Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a pot...
|
| T14298 |
Rimiducid
|
195514-63-7
|
98%
|
|
|
Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affin...
|
| T6629 |
PYR-41
|
418805-02-4
|
98%
|
|
|
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.
|
| T25212 |
CCCI-01
|
215778-97-5
|
98%
|
|
|
CCCI-01（Centrosome Clustering Chemical Inhibitor-01） is a centrosome cluster inhibitor. CCCI-01 has anticancer activity, induces apoptosis, and can be used in th...
|
| T5939 |
Calcium dobesilate
|
20123-80-2
|
98%
|
|
|
Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.
|
| T35610 |
2,5-dimethyl Celecoxib
|
457639-26-8
|
98%
|
|
|
2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1...
|
| T6207 |
SC144
|
895158-95-9
|
98%
|
|
|
SC144 is an orally active small-molecule gp130 inhibitor.
|
| T1123 |
Camptothecin
|
7689-03-4
|
98%
|
|
|
Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity. Cam...
|
| T3390 |
Obacunone
|
751-03-1
|
98%
|
|
|
Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compo...
|
| T9726 |
2’-OMe-Guanosine
|
2140-71-8
|
98%
|
|
|
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
|
| T6844 |
GGTI298 Trifluoroacetate
|
1217457-86-7
|
98%
|
|
|
GGTI298 Trifluoroacetate (GGTI 298 TFA salt) is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycl...
|
| T2502 |
INH1
|
313553-47-8
|
98%
|
|
|
INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.
|
| T2S1975 |
Ponicidin
|
52617-37-5
|
98%
|
|
|
Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens. Ponicidin exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer ...
|
| T7138 |
FB23-2
|
2243736-45-8
|
98%
|
|
|
FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).
|
| T0407 |
Edaravone
|
89-25-8
|
98%
|
|
|
Edaravone (MCI-186)(MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction.
|
| TN1804 |
Isosilybin A
|
142796-21-2
|
98%
|
|
|
Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC5...
|
| T13639 |
Deferasirox (Fe3+ chelate)
|
554435-83-5
|
98%
|
|
|
Deferasirox (Fe3+ chelate) is an orally available iron chelator with potential anticancer activity, inhibits the anti-apoptotic activity of MCL-1, and can be use...
|
| T13186 |
TL02-59
|
1315330-17-6
|
98%
|
|
|
TL02-59 is a selective inhibitor of Fgr in Src-family kinase (IC50 = 0.03 nM). TL02-59 inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. TL02-5...
|
