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Apoptosis

Apoptosis is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, DNA fragmentation, and mRNA decay.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T67930 CWI1-2 2408590-36-1 98%
CWI1-2 is a potent IGF2BP2 inhibitor that inhibits its interaction with M6A-modified target transcripts by binding IGF2BP2. CWI1-2 has anti-leukemic activity and...
T4123 LYN-1604 2088939-99-3 98%
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
T1934 Bay 11-7085 196309-76-9 98%
Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
T2S1008 Oxysophoridine 54809-74-4 98%
Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a pot...
T14298 Rimiducid 195514-63-7 98%
Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affin...
T6629 PYR-41 418805-02-4 98%
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.
TN1564 Delphinidin 3-glucoside chloride 6906-38-3 98%
Delphinidin 3-glucoside chloride (Delphinidin-3-O-glucoside chloride) is a dietary phenolic substance found in Hibiscus sabdariffa extracts. Delphinidin 3-glucos...
T35610 2,5-dimethyl Celecoxib 457639-26-8 98%
2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1...
T6207 SC144 895158-95-9 98%
SC144 is an orally active small-molecule gp130 inhibitor.
T3390 Obacunone 751-03-1 98%
Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compo...
T39189 3,4,5-Trihydroxycinnamic acid decyl ester 1770778-45-4 98%
3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor with anticancer activity that induces apoptosis.3,4,5-Trihydroxycinnamic acid decyl es...
T9726 2’-OMe-Guanosine 2140-71-8 98%
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
TN1013 Cucurbitacin D 3877-86-9 98%
Cucurbitacin D, a triterpenoid isolated from Ecballium elaterium (L.), exhibits anticancer and antitumor activity, inhibits glucose uptake and lactate production...
T33492 Methyl pyropheophorbide-a 6453-67-4 98%
Methyl pyropheophorbide-a (MPPa) is a chlorine photosensitizer and a derivative of chlorophyll a. It is photodynamically active, induces apoptosis and inhibits t...
TN1094 Ginsenoside Rg6 147419-93-0 98%
Ginsenoside Rg6 can inhibit JK cell proliferation in human lymphocytoma and induce its apoptosis, the mechanism may through mitochondrial dysfunction and an incr...
T2502 INH1 313553-47-8 98%
INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.
T2S1975 Ponicidin 52617-37-5 98%
Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens. Ponicidin exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer ...
T20025 Imipramine 50-49-7 98%
Imipramine (Dimipressin) is an orally active Fascin1 inhibitor with antidepressant and antitumor activity.Imipramine inhibits the 5-hydroxytryptamine transporter...
TN1252 3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone 1334309-44-2 98%
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone is a flavonoid from Morus alba that is cytotoxic and induces apoptosis.
T32105 Cipepofol 1637741-58-2 98%
Cipepofol (HSK3486) is a GABAA receptor agonist with sedative properties and protective effects in a variety of cardiovascular diseases.Cipepofol activates the S...
CWI1-2
T67930
CWI1-2 is a potent IGF2BP2 inhibitor that inhibits its interaction with M6A-modified target transcripts by binding IGF2BP2. CWI1-2 has anti-leukemic activity and...
LYN-1604
T4123
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
Bay 11-7085
T1934
Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
Oxysophoridine
T2S1008
Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a pot...
Rimiducid
T14298
Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affin...
PYR-41
T6629
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.
Delphinidin 3-glucoside chloride
TN1564
Delphinidin 3-glucoside chloride (Delphinidin-3-O-glucoside chloride) is a dietary phenolic substance found in Hibiscus sabdariffa extracts. Delphinidin 3-glucos...
2,5-dimethyl Celecoxib
T35610
2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1...
SC144
T6207
SC144 is an orally active small-molecule gp130 inhibitor.
Obacunone
T3390
Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compo...
3,4,5-Trihydroxycinnamic acid decyl ester
T39189
3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor with anticancer activity that induces apoptosis.3,4,5-Trihydroxycinnamic acid decyl es...
2’-OMe-Guanosine
T9726
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
Cucurbitacin D
TN1013
Cucurbitacin D, a triterpenoid isolated from Ecballium elaterium (L.), exhibits anticancer and antitumor activity, inhibits glucose uptake and lactate production...
Methyl pyropheophorbide-a
T33492
Methyl pyropheophorbide-a (MPPa) is a chlorine photosensitizer and a derivative of chlorophyll a. It is photodynamically active, induces apoptosis and inhibits t...
Ginsenoside Rg6
TN1094
Ginsenoside Rg6 can inhibit JK cell proliferation in human lymphocytoma and induce its apoptosis, the mechanism may through mitochondrial dysfunction and an incr...
INH1
T2502
INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.
Ponicidin
T2S1975
Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens. Ponicidin exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer ...
Imipramine
T20025
Imipramine (Dimipressin) is an orally active Fascin1 inhibitor with antidepressant and antitumor activity.Imipramine inhibits the 5-hydroxytryptamine transporter...
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone
TN1252
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone is a flavonoid from Morus alba that is cytotoxic and induces apoptosis.
Cipepofol
T32105
Cipepofol (HSK3486) is a GABAA receptor agonist with sedative properties and protective effects in a variety of cardiovascular diseases.Cipepofol activates the S...
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