Complement factor I Protein, Mouse, Recombinant (His)

Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 66.39 kDa and the accession number is Q61129.

Complement factor I Protein, Mouse, Recombinant (His)

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 112,000
500 μg	約5 days	￥ 447,500
1 mg	約5 days	￥ 746,000

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説明

Species	Mouse
Expression Host	HEK293 Cells
Tag	C-His
Accession Number	Q61129
別名	FIC3b-INA, I factor (complement), IF, C3B/C4B inactivator, C3BINA, CFI, KAF
Construction	Arg19-Val603
Protein Purity	> 90% as determined by Tris-Bis PAGE; > 90% as determined by HPLC
分子量	66.39 kDa (predicted). Due to autocatalytic cleavage and glycosylation, the protein migrates to 80-100 kDa on Tris-Bis PAGE result.

Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 150 mM NaCl (pH 8.0). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes.

参考文献

1. Lv W, et al. A novel complement factor I involving in the complement system immune response from Lampetra morii. Fish Shellfish Immunol. 2020 Mar;98:988-994. doi: 10.1016/j.fsi.2019.11.017. Epub 2019 Nov 8. PMID: 31712129.

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Complement factor I Protein, Mouse, Recombinant (His)

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