Fas Ligand Protein, Rat, Recombinant (His)

Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protein, Rat, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 21.3 kDa and the accession number is A0A0U5J7X8.

Fas Ligand Protein, Rat, Recombinant (His)

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 142,000

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説明

Species	Rat
Expression Host	P. pastoris (Yeast)
Tag	N-His
Accession Number	A0A0U5J7X8
別名	Fas ligand
Construction	Rat Faslg (NP_037040.1) (Leu104-Leu278)
Protein Purity	> 95 % as determined by SDS-PAGE.
分子量	21.3 kDa (predicted)

Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

参考文献

1. Pitti R M. et al., 1998, Nature. 396 (6712): 699-703. 2. Hane M. et al., 1995, FEBS Lett. 373 (3): 265-8. 3. Schneider P. et al., 1997, J Biol Chem. 272 (30): 18827-33.

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Fas Ligand Protein, Rat, Recombinant (His)

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