Galectin-3 Protein, Cynomolgus, Recombinant (His)

Galectin-3, also known as Mac-2, L29, CBP35, and epsilon BP, is classified as a chimeric member of the Galectin superfamily and contains one carbohydrate recognition domain (CRD) linked to a nonlectin domain.Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity).

Galectin-3 Protein, Cynomolgus, Recombinant (His)

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 112,000
500 μg	約5 days	￥ 447,500
1 mg	約5 days	￥ 746,000

バルクのお問い合わせ

説明

Species	Cynomolgus
Expression Host	HEK293 Cells
Tag	N-His
Accession Number	A0A2K5U233
別名	LGALS2, L29, AGE-R3, GALIG, Lectin L-29, MAC2GAL3, Mac-2, L31, CBP35, Gal-3, GALBPCBP35, LGALS3, Galectin3, galactin-3, GAL3
Construction	Ala2-Ile248
Protein Purity	> 95% as determined by Tris-Bis PAGE
分子量	27.05 kDa (predicted). Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.

Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Hepes, 150 mM NaCl, 200 mM L-arginine, 2 mM Tcep (pH 6.5). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in 50mM Hepes, 150mM NaCl, 200mM L-arginine, 2mM Tcep (pH 6.5). The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Galectin-3, also known as Mac-2, L29, CBP35, and epsilon BP, is classified as a chimeric member of the Galectin superfamily and contains one carbohydrate recognition domain (CRD) linked to a nonlectin domain.Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity).

参考文献

1. Dong R, et al. Galectin-3 as a novel biomarker for disease diagnosis and a target for therapy (Review)[J]. International Journal of Molecular Medicine, 2017.

Calculator

Reconstitution Calculator

Recombinant Proteins Dilute Calculator

Specific Activity Calculator

bottom

Galectin-3 Protein, Cynomolgus, Recombinant (His)

参考文献

Calculator

技術サポート

Keywords