| T21868 |
BIO-1211
|
187735-94-0
|
98%
|
|
|
BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).
|
| T14676 |
BMS-688521
|
893397-44-9
|
98%
|
|
|
BMS-688521 BMS-688521 is an orally active and potent inhibitor of LFA-1/ICAM interaction, a small molecule antagonist of leukocyte function-associated antigen-1 ...
|
| TP1879L1 |
P11 acetate
|
TP1879L1
|
98%
|
|
|
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).
|
| T76927 |
Bersanlimab
|
1987854-08-9
|
98%
|
|
|
Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties and can be u...
|
| T76924 |
Efalizumab
|
214745-43-4
|
98%
|
Efalizumab
|
|
Efalizumab, a novel potent regulator of T cells, is a humanized LFA-1 α subunit (CD11a) monoclonal antibody. Efalizumab has inhibitory effects on T cell activati...
|
| T76844 |
Abciximab
|
143653-53-6
|
98%
|
Abciximab
|
|
Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leuk...
|
| T9914 |
Vedolizumab
|
943609-66-3
|
98%
|
|
|
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.
|
| T6812L |
Cyclo(-RGDfK) TFA
|
500577-51-5
|
|
|
|
Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).
|
| T7570 |
RGD peptide (GRGDNP)
|
114681-65-1
|
|
|
|
RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.
|
| T4613 |
Arg-Gly-Asp TFA (99896-85-2(free base))
|
T4613
|
|
|
|
Arg-Gly-Asp TFA (99896-85-2(free base)) (RGD Trifluoroacetate) is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits ...
|
| T0342 |
Carvedilol phosphate hemihydrate
|
610309-89-2
|
100%
|
|
|
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
|
| TP1474 |
LXW7
|
1313004-77-1
|
100%
|
|
|
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (EC...
|
| TP1330 |
Cyclo(RADfK)
|
756500-23-9
|
100%
|
|
|
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.Cyclo(RADfK) is a neg...
|
| T13473 |
αvβ1 integrin-IN-1
|
1689540-62-2
|
100%
|
|
|
αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.
|
| T23796 |
BIRT-377
|
213211-10-0
|
100%
|
|
|
BIRT-377 is a negative allosteric and orally bioavailable inhibitor of ICAM-1 and LFA-1(Ki = 25.8 nM). BIRT-377 inhibits the production of IL-2 and can be used i...
|
| T27250L |
Elarofiban TFA
|
198958-89-3
|
100%
|
|
|
Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.
|
| T21781 |
A-286982
|
280749-17-9
|
97.24%
|
|
|
A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-...
|
| T16695 |
Pyrintegrin
|
1228445-38-2
|
97.81%
|
|
|
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances ...
|
| T6813 |
Cyclo(RGDyK) trifluoroacetate
|
250612-42-1
|
98%
|
|
|
Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
|
| T10397 |
ATN-161 trifluoroacetate salt
|
904763-27-5
|
98%
|
|
|
ATN-161 trifluoroacetate salt (ATN-161 TFA salt) is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases and improves survi...
|
