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gp130/IL6ST Protein, Human, Recombinant (His)

カタログ番号 TMPK-00412
別名: gp130, CD130, IL-6 R beta, IL6ST, IL-6R-β, IL-6R-beta, IL-6RB, gp130/CD130/IL-6 R β, CDw130, IL-6 R β

gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130. gp130/IL6ST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 68.94 kDa and the accession number is P40189-1.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
gp130/IL6ST Protein, Human, Recombinant (His)
パッケージサイズ 在庫状況 単価(税別)
100 μg 約5 days ¥ 85,500
500 μg 約5 days ¥ 342,000
1 mg 約5 days ¥ 569,500
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130. gp130/IL6ST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 68.94 kDa and the accession number is P40189-1.
Species Human
Expression Host HEK293 Cells
Tag C-His
Accession Number P40189-1
別名 gp130, CD130, IL-6 R beta, IL6ST, IL-6R-β, IL-6R-beta, IL-6RB, gp130/CD130/IL-6 R β, CDw130, IL-6 R β
Construction Glu23-Glu619
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 68.94 kDa (predicted). Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130.

参考文献

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Keywords

gp130/IL6ST Protein, Human, Recombinant (His) CD-130 gp130 CD130 IL-6 R beta IL6ST IL-6R-β IL-6R-beta IL-6RB gp130/CD130/IL-6 R β CDw130 IL-6 R β CD 130 recombinant recombinant-proteins proteins protein