Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocyte, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells.

Cat. No.	製品名	CAS No.	Purity	Chemical Structure
T6207	SC144	895158-95-9	98%
T6207	SC144 is an orally active small-molecule gp130 inhibitor.
T36526	IL-17 modulator 4	2446803-65-0	98%
T36526	IL-17 modulator 4 is a prodrug of IL-17 modulator 1 which is an efficacious modulator of IL-17.
T1813	VGX-1027	6501-72-0	98%
T1813	VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.
T10497	Benralizumab	1044511-01-4	98%
T10497	Benralizumab (MEDI-563) is a monoclonal antibody targeting the interleukin-5 receptor alpha (IL-5Rα). It enhances antibody-dependent cell-mediated cytotoxicity, ...
T76956	Vixarelimab	2243320-83-2	98%
T76956	Vixarelimab (KPL-716) is a human anti-oncostatin M (OSM) monoclonal antibody with affinity for the beta chain of the OSM receptor and inhibition of IL-31 and OSM...
T76910	Astegolimab	2173054-79-8	98%
T76910	Astegolimab (RG 6149) is a humanised IgG2 monoclonal antibody that targets the IL-33 receptor and inhibits IL-33 signalling. Astegolimab is used in the study of ...
T76891	Oxelumab	1186098-83-8	98%	Oxelumab
T76891	Oxelumab (R 4930) is a human monoclonal antibody for OX40L. Oxelumab could be used to study asthma.			Oxelumab
T76883	Talacotuzumab	1826831-79-1	98%	Talacotuzumab
T76883	Talacotuzumab (JNJ 56022473) is an IgG1 fully humanized CD123 neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has a high affin...			Talacotuzumab
T76775	Fezakinumab	1007106-86-6	98%	Fezakinumab
T76775	Fezakinumab is a potent monoclonal antibody to interleukin-22 (IL-22). Fezakinumab can be used to study immune system diseases and inflammation-related condition...			Fezakinumab
T76747	Fletikumab	1357158-22-5	98%	Fletikumab
T76747	Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid arthritis...			Fletikumab
T76724	Nemolizumab	1476039-58-3	98%	Nemolizumab
T76724	Nemolizumab (CIM331) is a humanized monoclonal antibody against human interleukin-31 receptor A that inhibits the binding and subsequent signal transduction of i...			Nemolizumab
T73698	Basiliximab	179045-86-4	98%	Basiliximab
T73698	Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody against the interleukin-2 receptor. Basiliximab has good immunosuppressive a...			Basiliximab
TN4379	Kansuinine A	57701-86-7	98%
TN4379	Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
T2061	APY0201	1232221-74-7	98%
T2061	APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (P...
T8033	Sodium Thiocyanate	540-72-7
T8033	Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.
T2893	Muscone	541-91-3
T2893	Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
T13375	YQ128	2454246-18-3
T13375	YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
T0304	Methylthiouracil	56-04-2	100%
T0304	Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
T0054	Disulfiram	97-77-8	95%
T0054	Disulfiram (TETD) is an inhibitor of the acetaldehyde dehydrogenase ALDH, inhibiting hALDH1 and hALDH2 (IC50=0.15/1.45 μM) with specificity. Disulfiram is acutel...
T38105	Ixekizumab	1143503-69-8	95.00%
T38105	Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM.Ixekizumab bloc...