Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 μg | 約5 days | ¥ 32,000 |
50 μg | 約5 days | ¥ 96,000 |
500 μg | 約5 days | ¥ 447,500 |
1 mg | 約5 days | ¥ 675,000 |
説明 | Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-6xHis |
Accession Number | P05556 |
別名 | Integrin Beta-1, VLA-4 Subunit β, Fibronectin Receptor Subunit Beta, Fibronectin Receptor Subunit β, CD29, ITGB1, Integrin β-1, VLA-4 Subunit Beta, FNRB, MDF2, MSK12 |
Amino Acid | Gln21-Asp728 |
Construction | Gln21-Asp728 |
Protein Purity | Greater than 90% as determined by reducing SDS-PAGE. Greater than 90% as determined by SEC-HPLC. |
分子量 | 100-130 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin. |
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Please read the User Guide of Recombinant Proteins for more specific information.
ITGB1 Protein, Human, Recombinant (aa 21-728, His) Integrin Beta-1 VLA-4 Subunit β ITGB 1 Integrin b-1 MDF 2 Fibronectin Receptor Subunit Beta Fibronectin Receptor Subunit β MSK-12 CD-29 CD29 ITGB1 Integrin β-1 VLA-4 Subunit Beta MDF-2 CD 29 FNRB MDF2 ITGB-1 MSK12 MSK 12 recombinant recombinant-proteins proteins protein