| 説明 |
BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family, which are involved in tumor development through the inhibition of caspases. Livin/BIRC7 is specifically over-expressed in ACC, suggesting that it might be involved in adrenocortical tumorigenesis and represent a new molecular marker of malignancy. |
| Species |
Human
|
| Expression Host |
E. coli
|
| Tag |
C-His
|
| Accession Number |
AAH14475.1
|
| 別名 |
MLIAP, baculoviral IAP repeat containing 7, RNF50, KIAP, ML-IAP, LIVIN
|
| Construction |
The Human BIRC7 (AAH14475.1) (Met1-Ser298)
|
| Protein Purity |
> 85 % as determined by SDS-PAGE
|
| 分子量 |
33.6 kDa (predicted)
|
| Endotoxin |
Please contact us for more information.
|
| Formulation |
Supplied as sterile 50 mM Tris, 200 mM NaCl, pH 8.0.
|
| Reconstitution |
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
|
| Stability & Storage |
It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
|
| Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
|
| Research Background |
BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family, which are involved in tumor development through the inhibition of caspases. Livin/BIRC7 is specifically over-expressed in ACC, suggesting that it might be involved in adrenocortical tumorigenesis and represent a new molecular marker of malignancy.
|
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