PPM1G Protein, Human, Recombinant (aa 317-546, His)

Protein phosphatase 1G, also known as Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, Protein phosphatase magnesium-dependent 1 gamma, PP2C-gamma, PPM1G and PPM1C, is a cytoplasm protein that belongs to the PP2C family. PPM1G / PP2C-gamma is widely expressed. It is most abundant in testis, skeletal muscle, and heart. Alternatively spliced transcript variants encoding the same protein have been described. PP2C family members are known to be negative regulators of cell stress response pathways. PPM1G / PP2C-gamma is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. PPM1G / PP2C-gamma also plays a role in regulating cell cycle progression.

PPM1G Protein, Human, Recombinant (aa 317-546, His)

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 161,000

バルクのお問い合わせ

説明

Species	Human
Expression Host	E. coli
Tag	N-His
Accession Number	O15355
別名	protein phosphatase, Mg2+/Mn2+ dependent, 1G, PP2Cγ, PPP2CG, PP2CGAMMA, PP2CG
Construction	The Human PPM1G (O15355) C-terminal fragment (Met 317-Asp 546) was expressed, with a polyhistidine tag at the N-terminus.
Protein Purity	> 95 % as determined by SDS-PAGE
分子量	26.6 kDa (predicted)

Endotoxin	Please contact us for more information.
Formulation	Supplied as sterile 50 mM Tris, 1 mM DTT, 20% glycerol, pH 7.5.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Protein phosphatase 1G, also known as Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, Protein phosphatase magnesium-dependent 1 gamma, PP2C-gamma, PPM1G and PPM1C, is a cytoplasm protein that belongs to the PP2C family. PPM1G / PP2C-gamma is widely expressed. It is most abundant in testis, skeletal muscle, and heart. Alternatively spliced transcript variants encoding the same protein have been described. PP2C family members are known to be negative regulators of cell stress response pathways. PPM1G / PP2C-gamma is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. PPM1G / PP2C-gamma also plays a role in regulating cell cycle progression.

参考文献

1. Travis S.M., et al., 1997, FEBS Lett. 412:415-9. 2. Molina H., et al., 2007, Proc. Natl. Acad. Sci. USA. 104: 2199-204. 3. Matsuoka S., et al., 2007, Science 316:1160-6.

Calculator

Reconstitution Calculator

Recombinant Proteins Dilute Calculator

Specific Activity Calculator

bottom

PPM1G Protein, Human, Recombinant (aa 317-546, His)

参考文献

Calculator

技術サポート

Keywords