As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in the degradative pathways.
説明 | As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in the degradative pathways. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-mFc |
Accession Number | AAH36460.1 |
別名 | thioredoxin-related transmembrane protein 1, PDIA11, TXNDC, TXNDC1, TMX |
Construction | The Human TMX1 (AAH36460.1) (Met1-Ser180) was expressed with the Fc region of Mouse IgG1 at the C-terminus. |
Protein Purity | > 90 % as determined by SDS-PAGE. |
分子量 | 44.4 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in the degradative pathways. |
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TMX1 Protein, Human, Recombinant (mFc) thioredoxin-related transmembrane protein 1 PDIA11 PDIA-11 TXNDC TXNDC-1 PDIA 11 TXNDC1 TMX TXNDC 1 recombinant recombinant-proteins proteins protein