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TNF alpha Protein, Canine, Recombinant

カタログ番号 TMPY-01594
別名: TNF-α, tumor necrosis factor

TNF alpha Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A9LMQ0.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
TNF alpha Protein, Canine, Recombinant
パッケージサイズ 在庫状況 単価(税別)
50 μg 約5 days ¥ 49,000
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 TNF alpha Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A9LMQ0.
Species Canine
Expression Host E. coli
Tag Tag Free
Accession Number A9LMQ0
別名 TNF-α, tumor necrosis factor
Construction The soluble form of canine TNFα (NP_001003244.4) (Val 77-Leu 233) was expressed, with an initial Met at the N-terminus.
Protein Purity > 96 % as determined by SDS-PAGE
分子量 17.3 kDa (predicted)
Endotoxin Please contact us for more information.
Formulation Supplied as sterile 50 mM Tris, 500 mM NaCl, 20% glycerol, pH 8.0.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & AntibodyCancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

参考文献

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Keywords

TNF alpha Protein, Canine, Recombinant TNF-α tumor necrosis factor recombinant recombinant-proteins proteins protein