Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. ZIKV has a more selective and larger impact on the expression of genes involved in DNA replication and repair. P53 inhibitors can block the apoptosis induced by ZIKV-M in hNPCs.
説明 | Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. ZIKV has a more selective and larger impact on the expression of genes involved in DNA replication and repair. P53 inhibitors can block the apoptosis induced by ZIKV-M in hNPCs. |
Species | ZIKV |
Expression Host | HEK293 Cells |
Tag | C-Fc |
Accession Number | ALU33341.1 |
Construction | The Zika virus (strain Zika SPH2015) M / Membrane (ALU33341.1) (Ala216-Ser290) was expressed with the Fc region of Human IgG1 at the C-terminus. |
Protein Purity | > 95 % as determined by SDS-PAGE. |
分子量 | 35.2 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. ZIKV has a more selective and larger impact on the expression of genes involved in DNA replication and repair. P53 inhibitors can block the apoptosis induced by ZIKV-M in hNPCs. |
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