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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T8684 | Sotorasib | AMG-510 | Ras |
Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib ... | |||
T22258 | (S)-AMG-510 | Ras | |
(S)-AMG-510 is an S-type compound of AMG-510, a potent covalent inhibitor of KRAS G12C with potential antitumor activity. |