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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T6719 | Varlitinib | ASLAN001,ARRY-334543 | HER |
Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively. | |||
T6763 | Xevinapant | ARRY-334543,SM-406,AT406,Debio-1143 | IAP |
Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, ... | |||
T20954 | Varlitinib Tosylate | Varlitinib-Tosylate,ARRY-334543 Tosylate,ARRY-543 Tosylate | |
Varlitinib Tosylate is a selective and potent inhibitor of ErbB1(EGFR) and ErbB2(HER2). |