ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T6712 | Tyrphostin AG 879 | 148741-30-4 | 98% |
|
| Tyrphostin AG 879 effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR. | ||||
| T12594 | Pyrotinib dimaleate | 1397922-61-0 | 98% |
|
| Pyrotinib dimaleate is a potent and selective dual inhibitor of EGFR/HER2 (IC50 s of 13 and 38 nM, respectively). | ||||
| T1291 | Cisapride | 81098-60-4 | 98% |
|
| Cisapride is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote intestinal pe... | ||||
| T11966 | MCHR1 antagonist 2 | 863115-70-2 | 98% |
|
| MCHR1 antagonist 2 also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells. MCHR1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, w... | ||||
| T4612 | NS309 | 18711-16-5 | 98% |
|
| NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK ... | ||||
| T12912 | Sigma-1 receptor antagonist 3 | 1639220-17-9 | 98% |
|
| Sigma-1 receptor antagonist 3 is a potent and selective antagonist of Sigma-1 (σ1) receptor(Ki : 1.14 nM), has the potential for the neuropathic pain. | ||||
| T2325 | Neratinib | 698387-09-6 | 98% |
|
| Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively. | ||||
| T8189 | Dihydroberberine | 483-15-8 | 98% |
|
| Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channel... | ||||
| T30260 | AZD-5672 | 780750-65-4 | 98% |
|
| AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM. AZD-5672 inhibits hERG cardiac ion channel binding and P-gp-mediated digoxin transport with IC50s of 7... | ||||
| T13088 | Tarloxotinib bromide | 1636180-98-7 | 98% |
|
| Tarloxotinib bromide is an irreversible inhibitor of EGFR/HER2. | ||||
| T7819 | TAS0728 | 2088323-16-2 | 98% |
|
| TAS0728 is a HER2 inhibitor, with antitumor activity | ||||
| T2630 | Poziotinib | 1092364-38-9 | 98% |
|
| Poziotinib(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM). | ||||
| T3673 | Mollugin | 55481-88-4 | 98% |
|
| Mollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for ... | ||||
| T2518 | ARRY-380 (analog ) | 937265-83-3 | 98% |
|
| ARRY-380 is a potent and selective HER2 inhibitor. | ||||
| T4S0544 | Furanodienone | 24268-41-5 | 98% |
|
| 1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienone inhibits EGFR/HER2 signaling pathway in... | ||||
| T3192 | NS1643 | 448895-37-2 | 98% |
|
| NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM. | ||||
| T4342 | PF-04929113 Mesylate | 1173111-67-5 | 98% |
|
| PF-04929113 Mesylate, a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37 nM). | ||||
| T34760 | SYR127063 | 871026-18-5 | 98% |
|
| SYR127063 (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation. | ||||
| T2034 | AG1557 | 189290-58-2 | 98% |
|
| AG-1557 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194). | ||||
| T6677 | Sophocarpine | 6483-15-4 | 98% |
|
| Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects. | ||||
