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Search Results for " Alpha-toxin "

ターゲット

9

阻害剤

19

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T80530 Spinoxin SPX,α-KTx6.13,Potassium channel toxin alpha-KTx 6.13 Potassium Channel
Spinoxin, a 34-residue peptide neurotoxin extracted from the venom of Heterometrus spinifer, is characterized by four disulfide bridges. It acts as a potent inhibitor of the Kv1.3 potassium channel with an IC 50 value of...
T13540 alpha-Amanitin α-Amatoxin,α-Amanitin Others
alpha-Amanitin (alpha-Amanitin) is the lethal toxin in Trichoderma viride and acts in vivo via the enterohepatic circulation and transport system. alpha-Amanitin induces cell death and can be used in the synthesis of ADC...
T14953 Chloroquinoxaline sulfonamide NSC-339004,Chloroquinoxaline Topoisomerase
Chloroquinoxaline sulfonamide (Chloroquinoxaline) is a topoisomerase II alpha/beta toxin with antitumor activity and immunosuppressive properties that inhibits the proliferation of B16 melanoma cells in mice, and can be ...
T22297 Clindamycin hydrochloride monohydrate Clindamycin alcoholate Antibiotic
Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentra...
T82949 Atidortoxumab
Atidortoxumab is a human monoclonal antibody (IgG1κ) targeting Staphylococcus aureus alpha toxin [1].
T81832 MC-VC-PABC-C6-alpha-Amanitin Others
MC-VC-PABC-C6-alpha-Amanitin is an antibody-drug conjugate that combines the anticancer toxin alpha-Amanitin with the monoclonal antibody MC-VC-PABC-C6. Alpha-Amanitin acts as a potent inhibitor of RNA polymerase IIα, en...
T80482 α-Conotoxin EIIB Alpha-conotoxin EIIB
Alpha-Conotoxin EIIB is a peptide toxin derived from Conus ermineus that selectively binds to neuronal nicotinic acetylcholine receptors (nAChR) with a dissociation constant (Ki) of 2.2 nM. This compound is utilized in n...
T76973 Tosatoxumab
Tosatoxumab (AR-301; KBSA301), a human immunoglobulin G1 monoclonal antibody, specifically targets and neutralizes S. aureus alpha-toxin (alpha-hemolysin; Hla) by binding to its N-terminal epitope. This interaction block...
T80034 Margatoxin TFA Potassium Channel
Margatoxin TFA, an alpha-KTx scorpion toxin isolated from Centruroides margaritatus venom, is a 39-amino-acid peptide that serves as a high-affinity inhibitor of Kv1.3 (Kd = 11.7 pM). It also inhibits Kv1.2 (Kd = 6.4 pM)...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-03522 Alpha-hemolysin Protein, S. aureus, Recombinant (His) Staphylococcus aureus P. pastoris (Yeast)
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl...
TMPH-03523 Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO) Staphylococcus aureus E. coli
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl...
TMPH-00054 AaH II Protein, Androctonus australis, Recombinant (His & SUMO) Androctonus australis E. coli
AaH II Protein, Androctonus australis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 23.3 kDa and the accession number is P01484.
TMPH-00837 BjaIT Protein, Hottentotta judaicus, Recombinant (His & Myc) Hottentotta judaicus E. coli
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against insects (para/tipE)....
TMPH-02404 LqhaIT Protein, Leiurus hebraeus, Recombinant (His & SUMO) Yellow scorpion E. coli
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. The dissociation is voltage-dependent. This toxin...
TMPH-00055 Alpha-toxin Amm8  Protein, Androctonus mauritanicus, Recombinant (His & Myc) Androctonus mauritanicus Baculovirus Insect Cells
Alpha-toxin Amm8  Protein, Androctonus mauritanicus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 11.3 kDa and the accession number is Q7...
TMPH-03625 Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc) Tityus serrulatus Baculovirus Insect Cells
Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 10.9 kDa and the accession number is P684...
TMPH-00421 Phospholipase C Protein, Clostridium perfringens, Recombinant (His) C.perfringens E. coli
Phospholipase C Protein, Clostridium perfringens, Recombinant (His) is expressed in E. coli.
TMPH-00430 VxXIIC Protein, Conus vexillum, Recombinant (His & Myc & SUMO) Conus vexillum E. coli
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-bet...
TMPK-01060 GFRAL/GFR alpha-like Protein, Human, Recombinant (hFc) Human HEK293 Cells
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-01058 GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-01053 GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-01319 GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi) Cynomolgus HEK293 Cells
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-01059 GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-01320 GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated Cynomolgus HEK293 Cells
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPK-01052 GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi) Mouse HEK293 Cells
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain...
TMPH-03652 Ustilago maydis P6 virus (UmV6) KP6 killer toxin (His) UmV6 P. pastoris (Yeast)
This protein is lethal to sensitive cells of the same or related species. The KP6 alpha subunit is known to recognize some cellular receptors before interaction of the complex with KP6 beta, precipitating cell death. Ust...
TMPY-00583 ADPRH Protein, Human, Recombinant (His) Human E. coli
Cholera toxin (CT) produced by Vibrio cholerae causes the devastating diarrhea of cholera by catalyzing the ADP-ribosylation of the alpha subunit of the intestinal Gs protein (Gsalpha), leading to characteristic water an...
TMPY-02246 HB-EGF Protein, Human, Recombinant Human Baculovirus Insect Cells
Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolyticall...
Alpha-hemolysin Protein, S. aureus, Recombinant (His)
TMPH-03522
Species: Staphylococcus aureus
Expression System: P. pastoris (Yeast)
Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO)
TMPH-03523
Species: Staphylococcus aureus
Expression System: E. coli
AaH II Protein, Androctonus australis, Recombinant (His & SUMO)
TMPH-00054
Species: Androctonus australis
Expression System: E. coli
BjaIT Protein, Hottentotta judaicus, Recombinant (His & Myc)
TMPH-00837
Species: Hottentotta judaicus
Expression System: E. coli
LqhaIT Protein, Leiurus hebraeus, Recombinant (His & SUMO)
TMPH-02404
Species: Yellow scorpion
Expression System: E. coli
Alpha-toxin Amm8  Protein, Androctonus mauritanicus, Recombinant (His & Myc)
TMPH-00055
Species: Androctonus mauritanicus
Expression System: Baculovirus Insect Cells
Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc)
TMPH-03625
Species: Tityus serrulatus
Expression System: Baculovirus Insect Cells
Phospholipase C Protein, Clostridium perfringens, Recombinant (His)
TMPH-00421
Species: C.perfringens
Expression System: E. coli
VxXIIC Protein, Conus vexillum, Recombinant (His & Myc & SUMO)
TMPH-00430
Species: Conus vexillum
Expression System: E. coli
GFRAL/GFR alpha-like Protein, Human, Recombinant (hFc)
TMPK-01060
Species: Human
Expression System: HEK293 Cells
GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi)
TMPK-01058
Species: Human
Expression System: HEK293 Cells
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-01053
Species: Mouse
Expression System: HEK293 Cells
GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi)
TMPK-01319
Species: Cynomolgus
Expression System: HEK293 Cells
GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-01059
Species: Human
Expression System: HEK293 Cells
GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
TMPK-01320
Species: Cynomolgus
Expression System: HEK293 Cells
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi)
TMPK-01052
Species: Mouse
Expression System: HEK293 Cells
Ustilago maydis P6 virus (UmV6) KP6 killer toxin (His)
TMPH-03652
Species: UmV6
Expression System: P. pastoris (Yeast)
ADPRH Protein, Human, Recombinant (His)
TMPY-00583
Species: Human
Expression System: E. coli
HB-EGF Protein, Human, Recombinant
TMPY-02246
Species: Human
Expression System: Baculovirus Insect Cells