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TP1232 |
Amylin, amide, rat
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Amylin (rat) |
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Amylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a con... |
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TP1233 |
Amylin (8-37), rat
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Amylin (8-37) (mouse, rat) |
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Amylin (8-37), rat is a truncated analog of native Amylin that selectively inhibits insulin-related glucose uptake and glycogen deposition in muscle tissue. Amylin is also known as islet amyloid precursor peptide (IAPP) ... |
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T38764 |
Amylin (8-37), human
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Amylin (8-37), human, derived from human Amylin, possesses direct vasodilator effects in isolated mesenteric resistance arteries of rats. Human Amylin is a small pancreatic β-cell hormone that forms aggregates in the abs... |
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TP1519 |
Amylin (IAPP), feline
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Amylin (IAPP), feline is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas. |
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TP1183 |
Amylin, amide, human
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DAP amide, human |
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Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin res... |
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T75787 |
Amylin, amide, human TFA
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Amylin, amide, human TFA, a 37-amino acid polypeptide, functions as a pancreatic hormone that is cosecreted with insulin, playing distinct roles in metabolism and glucose homeostasis. It regulates blood sugar by inhibiti... |
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T76478 |
Amylin (8-37) (human)
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Amylin (8-37) (human) (hIAPP (8-37)) represents the 8-37 fragment of human islet amyloid polypeptide (IAPP). This assembly exhibits a duplex folding with a hairpin structure [1]. |
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T76480 |
Amylin (1-37) (human)
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Amylin (1-37) (human) (hIAPP (1-37)), a peptide hormone found in pancreatic beta-cell secretory granules, features an amidated C-terminus and a disulfide bond between cysteine residues 2 and 7 [1]. |
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T76028 |
Amylin (IAPP), feline TFA
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Amylin (IAPP), feline TFA, a 37-amino acid polypeptide derived from felines, stands as a principal secretion product of the pancreatic islets' β-cells. This regulatory peptide notably inhibits the secretion of insulin an... |
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T76645 |
Acetyl-Amylin (8-37) (human)
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Acetyl-Amylin (8-37) (human) is a specific amylin antagonist [1] . |
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T81678 |
NF(N-Me)GA(N-Me)IL
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Amylin (22-27) [NMeG24, NMeI26], human (IAPP) |
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NF(N-Me)GA(N-Me)IL is a biologically active peptide, representing a modified segment (amino acids 22 to 27) of the human islet amyloid polypeptide (hIAPP) sequence NFGAIL. This modification includes N-methylations at G24... |
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TP2135L |
CAC 253 acetate
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cAC 253 acetate (TP2135 Free base) |
Amylin Receptor
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cAC 253 acetate (TP2135 Free base) is an amylin antagonist. cAC 253 acetate inhibits 125I-adrenomedullin binding, with an IC50 of 25 nM. |
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TP2320 |
Pramlintide acetate(151126-32-8 free base)
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Others
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Pramlintide acetate is a polypeptide analogue of human amylin. It serves as an antidiabetic agent and exhibits antineoplastic activity in colorectal cancer. |
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TP1257 |
Adrenomedullin (AM) (22-52), human
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22-52-Adrenomedullin (human) |
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Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin. |
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T38998 |
Pramlintide
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Pramlintide, a polypeptide analog of human amylin, is an antidiabetic agent with antineoplastic properties in colorectal cancer. |
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T75934 |
AC 187 TFA
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AC 187 TFA, a potent and orally active amylin receptor antagonist, exhibits an IC50 of 0.48 nM and a Ki of 0.275 nM. It demonstrates greater selectivity for the amylin receptor over calcitonin and CGRP receptors and has ... |
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T36911 |
Pramlintide (acetate hydrate)
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Others
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Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormone amylin that contains proline residues substituted at positions 25, 28, and 29. It stimulates cAMP production in HEK293 cells expressing human ... |
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TP2135 |
CAC 253
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Amylin (AMY3) antagonist (IC50 = 0.3 μM). Protects neuronal cells from Aβ(1-42)-induced cytotoxicity in vitro. Brain penetrant. Improves spatial memory and reduces Aβ plaque number and total area in a mouse Alzheimer's d... |
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T76262 |
Cagrilintide
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Cagrilintide, an investigational novel long-acting acylated amylin analogue, functions as an agonist for nonselective amylin receptors (AMYR) and the calcitonin G protein-coupled receptor (CTR). It significantly reduces ... |
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T75709 |
Pramlintide TFA
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Pramlintide TFA, a polypeptide analogue of human amylin and an antidiabetic agent, exhibits antineoplastic properties in colorectal cancer [1]. |
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TP2078 |
AC 253
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Amylin (AMY3) receptor antagonist. Inhibits andrenomedulin-stimulated cAMP production in vitro. Protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death ... |
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TP1677 |
Calcitonin (8-32), salmon
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Calcitonin (8-32), salmon is a highly selective amylin receptor antagonist.Calcitonin is a hormone known to participate in calcium and phosphorus metabolism. In mammals, the major source of calcitonin is from the parafol... |
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T36555 |
Tyr-α-CGRP (human) (trifluoroacetate salt)
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Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respecti... |
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T37413 |
Calcitonin (salmon) (trifluoroacetate salt)
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Others
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Calcitonin is a peptide hormone that lowers blood calcium level and inhibits bone resorption. It belongs to the calcitonin family of peptides, which also includes amylin , calcitonin gene-related peptide , and adrenomedu... |
