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T8682 |
Vazegepant hydrochloride
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Vazegepant HCl |
CGRP Receptor
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Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study. |
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T17194 |
Ubrogepant
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MK-1602 |
CGRP Receptor
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Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies. |
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TP1040 |
Calcitonin (salmon)
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Calcitonin salmon,Salmon calcitonin |
CGRP Receptor
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Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause. |
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T12293L |
Olcegepant
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BIBN-4096,BIBN 4096BS |
CGRP Receptor
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Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP). |
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T4610 |
Rimegepant
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BMS 927711,BMS-927711,BMS927711,BHV-3000 |
CGRP Receptor
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Rimegepant (BMS 927711) is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM. |
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T6590 |
MK-3207 Hydrochloride
|
MK-3207 HCl |
CGRP Receptor
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MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2. |
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T13453 |
CGRP antagonist 1
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|
CGRP Receptor
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CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for the study of cardiovascular and neurovascular diseases. |
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TP1323 |
CGRP 8-37 (rat)
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|
CGRP Receptor
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CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects that induces arterial relaxation. |
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TP1200 |
CGRP (83-119), rat TFA
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Calcitonin Gene Related Peptide(83-119), rat TFA |
Others
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CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor. |
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T38734 |
Vazegepant
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Zavegepant,BHV-3500,BMS-742413 |
CGRP Receptor
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Vazegepant (Zavegepant) is an orally available and selective antagonist of the calcitonin gene-related peptide CGRP receptor for pain relief and may be used in the study of migraine. |
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TP1134L |
HCGRP-(8-37) acetate
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HCGRP-(8-37) acetate (119911-68-1 free base) |
CGRP Receptor
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HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor. |
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TP1257L |
Adrenomedullin (AM) (22-52), human acetate
|
Adrenomedullin (AM) (22-52), human acetate（159899-65-7 Free base） |
CGRP Receptor
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T70820 |
MK-8825
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|
Others
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MK-8825 is a CGRP receptor antagonist. |
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TP1134 |
HCGRP-(8-37)
|
Human α-CGRP (8-37) |
|
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Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist |
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T16093 |
Telcagepant
|
MK-0974 |
Others
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T30537 |
BMS-694153
|
BMS694153,BMS 694153 |
Others
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BMS-694153 is a potent and selective CGRP receptor antagonist. |
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TP2044 |
α-CGRP(human)
|
α-CGRP (human) |
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Endogenous calcitonin gene-related peptide receptor (CGRP) agonist. |
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T75978 |
β-CGRP, human TFA
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|
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Human β-CGRP TFA (β-CGRP, human TFA) is a calcitonin peptide that functions through interaction with the calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP) complex, demonstrating IC50... |
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T76363 |
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat
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|
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[Tyr22] Calcitonin Gene Related Peptide (22-37), rat, refers to a fragment (amino acids 22-37) of the rat calcitonin gene-related peptide (CGRP) that targets the CGRP receptor and adenylate cyclase. While calcitonin is p... |
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T39522 |
HTL22562
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|
Others
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HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine. |
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TP1203 |
CGRP(83-119), rat
|
Calcitonin Gene Related Peptide (CGRP) (83-119), rat |
|
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Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor. |
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T26796 |
BI-44370
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|
Others
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|
BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain. |
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T12293 |
Olcegepant hydrochloride
|
BIBN-4096 hydrochloride,BIBN4096BS hydrochloride |
Others
|
|
Olcegepant hydrochloride is a potent and selective non-peptidethe calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (with IC50 of 0.03 nM for human CGRP). |
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T73703 |
(3R,5R,6S)-Atogepant
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|
Others
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Atogepant ((3R,5R,6S)-MK-8031) is the enantiomer of itself and serves as a calcitonin gene-related peptide (CGRP) receptor antagonist, primarily utilized in migraine research. |
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TP1131 |
β-CGRP, human TFA (101462-82-2 free base)
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CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA |
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β-CGRP,human tissue is one of the calcitonin peptide, through complex behavior of calcitonin receptor like receptor (CRLR) - and receptor activity - modifying proteins (increased), and 1 and 300 - nM CRLR IC50s/RAMP1 and... |
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T21558 |
MK-3207
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|
Others
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|
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC 50 = 0.12 nM; K i = 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3. IC50 Value: 0.024 nM (Ki, Human CGRP) [1] As other CGRP recep... |
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T76678 |
Eptinezumab
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|
|
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Eptinezumab, a human monoclonal antibody, specifically binds to and blocks the calcitonin gene-related peptide (CGRP) from binding to its receptor, thus acting as a preventive treatment for migraine in adults [1]. |
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T75934 |
AC 187 TFA
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|
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AC 187 TFA, a potent and orally active amylin receptor antagonist, exhibits an IC50 of 0.48 nM and a Ki of 0.275 nM. It demonstrates greater selectivity for the amylin receptor over calcitonin and CGRP receptors and has ... |
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TP2049 |
CRSP-1
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Endogenous central calcitonin (CT) receptor agonist that stimulates cAMP formation at a potency 350-fold greater than CT (ED50 values are 0.2 and 71 nM respectively). Displays no activity at calcitonin-gene related pepti... |
