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T41321 |
Docosahexaenoic acid ethyl ester
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Ethyl docosahexaenoate |
Dopamine Receptor
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Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) enhances 6-hydroxydopamine-induced neuronal damage by inducing lipid peroxidation in the mouse striatum, and can be used to study oxidative diseases of the retina... |
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T19294 |
Docosahexaenoic Acid methyl ester
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Methyl docosahexaenoate,all cis-DHA methyl ester |
Others
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Docosahexaenoic Acid methyl ester (all cis-DHA methyl ester) is a methylated docosahexaenoic acid analog that can be inserted into membrane phospholipids without being oxidized or hydrolyzed. |
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T36868 |
4-oxo Docosahexaenoic Acid
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Others
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4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF,... |
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T37633 |
17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
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Others
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17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2... |
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T84487 |
17(S)-HpDHA
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17(S)-hydroperoxy Docosahexaenoic Acid |
Others
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17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it eff... |
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T85270 |
Docosahexaenoic Acid Alkyne
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Click Tag™ DHA Alkyne,FA 22:8 |
Others
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Docosahexaenoic acid alkyne, an ω-alkyne derivative of docosahexaenoic acid, enables Cu(I)-catalyzed cycloaddition with azide-containing molecules for efficient click chemistry applications. It can be further utilized to... |
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T70005 |
LY3325656
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Others
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LY3325656 is a GPR142 agonist suitable for clinical testing in human. LY3325656 demonstrated anti-diabetic benefits in pre-clinical studies and
ADME/PK properties suitable for human dosing. LY3325656 is the first GPR1... |
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T19331 |
F 16915
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Others
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F 16915 can prevent heart failure-induced atrial fibrillation.F 16915 is a docosahexaenoic acid derivative. |
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T12707 |
Resolvin D2
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RvD2 |
Others
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Resolvin D2 is a docosahexaenoic acid (DHA) metabolite, with anti-inflammatory and anti-infective activities. |
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T41059 |
Resolvin D3
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RvD3 |
Others
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Resolvin D3 (RvD3) is a dysregulated mediator originating from docosahexaenoic acid (DHA). It plays a crucial role in reducing arthritic inflammation. |
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T36663 |
Decanoyl-L-carnitine (chloride)
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Others
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Decanoyl-L-carnitine is an ester derivative of L-carnitine . It increases the formation of C24 fatty acid intermediates, as well as docosapentaenoic and docosahexaenoic acid in rat hepatocytes. |
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T35997 |
22-HDHA
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Others
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22-HDHA is an oxidation product of docosahexaenoic acid . In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 micr... |
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T37225 |
(±)7(8)-DiHDPA
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Others
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(±)7(8)-DiHDPA is a major metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases. Epoxygenase metabolites of DHA, including (±)7(8)-DiHDPA, suppress aggregation and thromboxane ... |
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T35495 |
(±)13(14)-DiHDPA
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Others
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(±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases. Epoxygenase metabolites of DHA, including (±)13(14)-DiHDPA, are reported to inhibit angiogenesis, t... |
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T37371 |
4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid
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Others
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4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid is an unusual polyunsaturated fatty acid (PUFA) generated during the synthesis of docosahexaenoic acid-d5 . While the physiological properties of this compound are not ... |
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T85229 |
1,3-Dipalmitoyl-2-Docosahexaenoyl Glycerol
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TG(16:0/22:6/16:0),1,3-Palmitin-2-Docoahexaenoin,16:0/22:6/16:0-TG |
Others
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1,3-Dipalmitoyl-2-docosahexaenoyl glycerol, a triacylglycerol, features palmitic acid at the sn-1 and sn-3 positions and docosahexaenoic acid at the sn-2 position. Its dietary administration (30 g/kg) has been shown to d... |
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T85225 |
1,2-Dioleoyl-3-Docosohexaenoyl-rac-glycerol
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1,2-Olein-3-Docosohexaenoin,C1OO,TG(18:1/18:1/22:6),18:1/18:1/22:6-TG |
Others
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1,2-Dioleoyl-3-docosohexaenoyl-rac-glycerol, a triacylglycerol, consists of oleic acid at the sn-1 and sn-2 positions and docosahexaenoic acid at the sn-3 position. This compound has been identified in human breast milk. |
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T36607 |
(±)8-HDHA
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Others
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(±)8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)8-HDHA is a potential marker of oxidative stress... |
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T35492 |
(±)10(11)-DiHDPA
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Others
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(±)10(11)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid . It has been shown to inhibit VEGF-induced angiogenesis in mice and may have additional anti-inflammatory and anti-tumor effec... |
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T35512 |
(±)16-HDHA
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Others
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(±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)16-HDHA is a potential marker of oxidative stre... |
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T35504 |
(±)10-HDHA
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Others
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(±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.[1][2] It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.[3][4][5] (±)10-HDHA is a potential marker of... |
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T35508 |
(±)13-HDHA
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Others
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(±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Fresh water hydra was shown to metabolize DHA to 1... |
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T84990 |
1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-PE
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1-Hexadecanoyl-2-(Docosahexaenoyl)-sn-glycero-3-Phosphatidylethanolamine |
Others
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1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-PE, a phospholipid comprising palmitic acid (at the sn-1 position) and docosahexaenoic acid (at the sn-2 position), is present in the nucleus of mouse liver but absent from mito... |
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T37169 |
Resolvin D2 methyl ester
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Others
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Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. It evokes diverse anti-inflammatory effects which may mediate the resolution of infla... |
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T37168 |
Resolvin D1 methyl ester
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Resolvin D1 methyl ester |
Others
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Resolvin D1 is produced physiologically from the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase . It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in a... |
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T37532 |
Docosahexaenoyl Glycine
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The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina an... |
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T36042 |
17(R)-HDHA
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Others
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Resolvins are a group of polyhydroxylated metabolites of docosahexaenoic acid (DHA) found in the inflammatory exudates of aspirin-treated experimental animals. 17(R)-HDHA is the primary oxygenation product of DHA when ex... |
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T37289 |
Resolvin D2 n-3 DPA
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Resolvin D2 n-3 DPA |
Others
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Resolvin D2 n-3 DPA (RvD2 n-3 DPA) is a specialized pro-resolving mediator (SPM).1It is formed from docosapentaenoic acid , an intermediate in the conversion of eicosapentaenoic acid to docosahexaenoic acid , in human le... |
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T36606 |
(±)7-HDHA
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Others
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(±)7-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Enzymatic transformation of DHA by RBL-1 cells and ... |
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T36602 |
(±)4-HDHA
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Others
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(±)4-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Enzymatic transformation of DHA by RBL-1 cells also... |
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T36218 |
19R(20S)-EpDPA
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Others
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19R(20S)-EpDPA is an oxylipin and a metabolite of docosahexaenoic acid .1,2It is formed from DHA by various cytochrome P450 (CYP) isoforms in a stereoselective manner.219R(20S)-EpDPA (30 nM) prevents calcium-induced incr... |
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T37301 |
PCTR2
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Others
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Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutath... |
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T37302 |
PCTR3
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Others
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Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutath... |
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T35947 |
17(S)-HDHA
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Others
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17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain. 17(S)-HDHA serves as a precursor to 17(S)-resolvins and has intrinsic biological activity,... |
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T36426 |
Eicosapentaenoyl 1-propanol-2-amide
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Others
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Monoacylglycerols (MAGs) of ω-3 polyunsaturated fatty acids have diverse physiological and health effects. In particular, MAGs containing docosahexaenoic acid or eicosapentaenoic acid have anti-proliferative properties a... |
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T37240 |
(±)4(5)-DiHDPA lactone
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Others
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(±)5(6)-DiHET lactone is a 1,5 cyclic ester derived from (±)5(6)-DiHET , which, in turn, is a potential derivative of epoxidation of arachidonic acid at the α-5 double bond. (±)4(5)-DiHDPA lactone is a derivative of doco... |
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T84397 |
Heneicosapentaenoic Acid ethyl ester
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HPA ethyl ester |
Others
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Heneicosapentaenoic Acid (HPA), a 21:5 ω-3 fatty acid, is found in minute quantities in green algae and fish oils, resembling eicosapentaenoic acid (EPA) but with an added carbon on the carboxyl end, positioning the init... |
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T35505 |
(±)11-HDHA
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Others
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(±)11-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. DHA is metabolized to 11(S)-HDHA by human platelet... |
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T37259 |
14(S)-HDHA
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Others
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Docosahexaenoic acid is a nutritionally-derived ω-3 fatty acid that is abundant in the brain and the retina and is thought to be important in early development and for therapeutic approaches to inflammatory disorders and... |
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T84469 |
Heneicosapentaenoic Acid methyl ester
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HPA methyl ester |
Others
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Heneicosapentaenoic Acid (HPA) is a fatty acid found in small amounts in Bryopsis pennata Lamouroux green algae and fish oils, with a structure similar to eicosapentaenoic acid (EPA), but with an additional carbon at the... |
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T37238 |
(±)19(20)-EpDPA
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Others
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EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de... |
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T35509 |
(±)14-HDHA
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Others
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(±)14-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. DHA is metabolized to 14(S)-HDHA by human platelet... |
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T36601 |
(±)17-HDHA
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Others
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(±)17-HDHA is an autoxidation product of docosahexaenoic acid in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. 17(S)-HDHA could be produced by enzymatic oxidation of D... |
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T37503 |
Maresin 2
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3R,14S-diHDHA |
Others
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Docosahexaenoic acid is an ω-3 fatty acid that is abundant in the brain and the retina and is known to be important in early development.[1] [2] Maresin 2 (MaR2) is a 13R,14S-dihydroxy DHA formed by recombinant human mac... |
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T38208 |
Heneicosapentaenoic Acid
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Others
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Heneicosapentaenoic Acid (HPA) is a 21:5 ω-3 fatty acid present in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA) except elongated with one... |
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T37234 |
(±)14(15)-EpETE
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Others
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EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de... |
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T70006 |
DHA-paclitaxel
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Others
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DHA-paclitaxel, also know as Taxoprexin, is prodrug comprised of the naturally occurring omega-3 fatty acid docosahexaenoic acid (DHA) covalently conjugated to the anti-microtubule agent paclitaxel. Because tumor cells t... |
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T37300 |
PCTR1
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PCTR1 |
Others
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Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by ... |
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T38222 |
N-(α-Linolenoyl) Tyrosine
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Certain chronic neurologic disorders, such as Parkinson's disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons. N-(α-Linolenoyl) ... |
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T35493 |
(±)10(11)-EpDPA
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Others
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Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 10,11-double bo... |
