Dystrophin | TargetMol

カタログ番号	製品名	別名	ターゲット
T3424	Ezutromid	BMN 195,VOX-C1100,SMT C1100	Others
	Ezutromid (BMN 195) is a translation modulator of Small utrophin (EC50: 0.4 uM). Ezutromid is an orally bioavailable small molecule that transcriptionally upregulates the utrophin gene, increasing both utrophin mRNA and ...		Others
T39455	Viltolarsen	NS-065,NCNP-01	Others
	Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide that specifically targets the splicing of exon 53 in the dystrophin gene. It is utilized in research related to Duchenne muscular ...		Others
T84749	Drisapersen	Kyndrisa,GSK2402968A,PRO051	Others
	Drisapersen, an antisense oligonucleotide, facilitates exon 51 skipping in dystrophin pre-mRNA splicing, enabling the production of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with suita...		Others
T38860	Golodirsen	Golodirsen,SRP-4053	Others
	Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) designed to selectively bind and target exon 53 of dystrophin pre-mRNA, with applications in the investigation of Duchenne muscular dystrophy (DMD).		Others
T38859	Casimersen	SRP-4045	Others
	Casimersen (SRP-4045) is an antisense oligonucleotide, specifically belonging to the phosphorodiamidate morpholino oligomer subclass. It binds to exon 45 of dystrophin pre-mRNA, effectively restoring the open-reading fra...		Others
T34425	RTC13	Read-through compound 13,RTC 13,RTC-13	Others
	RTC13, as a premature termination codon (PTC) readthrough inducer, can act by restoring dystrophin expression and improving muscle function in the mdx mouse model for Duchenne muscular dystrophy.		Others
T34426	RTC14	Read-through compound-14,RTC 14,RTC-14,Read-through compound 14	Others
	RTC14, as a premature termination codon (PTC) readthrough inducer, can act by restoring dystrophin expression and improving muscle function in the mdx mouse model for Duchenne muscular dystrophy.		Others
T66481	TG-693		Others
	TG693, an orally available inhibitor of CLK1, promotes the skipping of the endogenous mutated exon 31 in Duchenne muscular dystrophy (DMD) patient-derived cells and increased the production of the functional exon 31-skip...		Others

Compounds

Ezutromid

T3424

Synonym: BMN 195,VOX-C1100,SMT C1100

Target: Others

Viltolarsen

T39455

Synonym: NS-065,NCNP-01

Target: Others

Drisapersen

T84749

Synonym: Kyndrisa,GSK2402968A,PRO051

Target: Others

Golodirsen

T38860

Synonym: Golodirsen,SRP-4053

Synonym: Read-through compound 13,RTC 13,RTC-13

Target: Others

RTC14

T34426

Synonym: Read-through compound-14,RTC 14,RTC-14,Read-through compound 14

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-03280	Dystrophin Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variet...
TMPH-03202	DAG1 Protein, Rabbit, Recombinant (His)	Rabbit	E. coli
	DAG1 Protein, Rabbit, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 73.5 kDa and the accession number is Q28685.
TMPH-01258	DAG1 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epi...
TMPY-00384	DAG1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	DAG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 79.7 kDa and the accession number is A0A024R2W4.
TMPH-03752	KRT8 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
TMPH-01579	KRT19 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. KRT19 Protein, Human, Recombinant (His & Myc) is expressed in Bac...
TMPH-01580	KRT19 Protein, Human, Recombinant (His)	Human	E. coli
	Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. KRT19 Protein, Human, Recombinant (His) is expressed in E. coli e...
TMPH-01365	SNTG1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May participate in...