Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ezutromid (BMN 195) is a translation modulator of Small utrophin (EC50: 0.4 uM). Ezutromid is an orally bioavailable small molecule that transcriptionally upregulates the utrophin gene, increasing both utrophin mRNA and protein. Through this action, Ezutromid increases muscle function in dystrophin-deficient MDX mice, a mouse model of muscular dystrophy.
説明 | Ezutromid (BMN 195) is a translation modulator of Small utrophin (EC50: 0.4 uM). Ezutromid is an orally bioavailable small molecule that transcriptionally upregulates the utrophin gene, increasing both utrophin mRNA and protein. Through this action, Ezutromid increases muscle function in dystrophin-deficient MDX mice, a mouse model of muscular dystrophy. |
ターゲット&IC50 | Small utrophin:0.4 μM |
別名 | BMN 195, VOX-C1100, SMT C1100 |
分子量 | 337.39 |
分子式 | C19H15NO3S |
CAS No. | 945531-77-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12 mg/mL (35.57 mM), Sonication is recommended.
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Ezutromid 945531-77-1 Others VOX-C-1100 BMN-195 BMN 195 Inhibitor dystrophy VOX-C1100 benzoxazole BMN195 inhibit VOX-C 1100 SMT C 1100 microsomes liver muscular Duchenne metabolite SMT C1100 SMT C-1100 inhibitor