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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T16380 | OGT 2115 | Others | |
OGT 2115 is an inhibitor of heparanase (IC50 = 0.4 µM), an enzyme that cleaves heparan sulfate into glucuronic acid (GlcUA) and N-acetylglucosamine (GlcNAc). OGT 2115 also showed antiangiogenic properties (IC50=1 μM). | |||
T69224 | Hemisurfen | ||
Hemisurfen is a small molecule, surfen derivative with heparan sulfate antagonist properties. | |||
T36111 | L-Iduronic acid sodium salt | ||
L-Iduronic acid sodium salt is a monosaccharide that is an important component of glycosaminoglycans (GAGs) such as heparin, heparan sulfate, and dermatan sulfate. | |||
TP1555 | Fibronectin Active Fragment Control | ||
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins.In addition to integrins, fibronectin also binds extracellular matrix ... | |||
T81940 | Lepunafusp alfa | JR-171 | |
Lepunafusp alfa (JR-171) is a blood-brain barrier-penetrating fusion protein comprising J-Brain Cargo and α-L-iduronidase (IDUA), a lysosomal enzyme. This compound effectively lowers the levels of heparan sulfate (HS) an... | |||
T81573 | Pabinafusp alfa | JR-141 | |
Pabinafusp alfa (JR-141), a transferrin receptor-targeting antibody fusing Iduronate 2-sulfatase with an anti-human transferrin receptor antibody, penetrates the blood-brain barrier and inhibits heparan sulfate (HS) accu... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T19355 | Heparan Sulfate | FGFR , Wnt/beta-catenin , Endogenous Metabolite | |
Heparan Sulfate, a complex and linear polysaccharide, forms a component of glycoproteins called heparan sulfate proteoglycans, abundantly expressed on the cell surface and within the extracellular matrix. | |||
T4825 | D-(+)-Xylose | D(+)-Xylose,(+)-Xylose,Wood sugar | Endogenous Metabolite |
D-(+)-Xylose (Wood sugar) is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucrose. Xylose is also found in mucopo... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-00290 | HS3ST1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
HS3ST1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 36 kDa and the accession number is AAH57803.1. | |||
TMPJ-00561 | SDC2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Syndecan-2 is a member of the Syndecans family comprised of type I transmembrane heparan sulfate proteoglycans (HSPG) that are involved in the regulation of many cellular processes. Four sub-types of mammalian Syndecans ... | |||
TMPY-02907 | FGF-19 Protein, Human, Recombinant | Human | E. coli |
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inclu... | |||
TMPJ-00137 | APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to relea... | |||
TMPJ-00865 | VEGF121 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD... | |||
TMPY-00828 | Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfat... | |||
TMPJ-00375 | HGF Protein, Human, Recombinant (His) | Human | HEK293 Cells |
HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propepti... | |||
TMPJ-00863 | GNS Protein, Human, Recombinant (His) | Human | HEK293 Cells |
N-Acetylglucosamine-6-Sulfatase is a member of the Sulfatase family. N-Acetylglucosamine-6-Sulfatase is required for the lysosomal degradation of the Glycosaminoglycans (GAG) Heparan Sulfate and Keratan Sulfate. N-Acetyl... | |||
TMPH-02878 | PTPRS Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects... | |||
TMPH-02293 | UGDH Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role i... | |||
TMPH-03658 | Vaccinia virus (strain Copenhagen) Ag35 Protein (His & Myc) | VACV | E. coli |
Envelope protein that binds to heparan sulfate on the cell surface and might provide virion attachment to target cell. Vaccinia virus (strain Copenhagen) Ag35 Protein (His & Myc) is expressed in E. coli expression system... | |||
TMPH-01221 | GLCE Protein, Human, Recombinant (His) | Human | E. coli |
Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine t... | |||
TMPK-01310 | Syndecan-1 Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells |
CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and ... | |||
TMPH-01447 | Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein C (His) | HHV-2 | E. coli |
Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Plays also a role in host immune evasion by inhibiting the host complement cascade activation. Human her... | |||
TMPH-01671 | Human metapneumovirus (strain CAN97-83) Fusion glycoprotein F0 (His & SUMO) | HMPV | E. coli |
Inactive precursor that is cleaved to give rise to the mature F1 and F2 fusion glycoproteins.; Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native st... | |||
TMPJ-01368 | GPC1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfa... | |||
TMPJ-00128 | SLAMF2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD48 is a GPI-linked protein in the CD2 family of immunoglobulin superfamily proteins. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic prog... | |||
TMPH-01080 | Ceruloplasmin Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the ... | |||
TMPJ-01433 | Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated | Human | E. coli |
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components ... | |||
TMPJ-01317 | EXTL2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Exostosin-like 2 (EXTL2) is a member of the exostosin (EXT)-related family which contains five members: EXT1, EXT2, EXTL1, EXTL2, and EXTL3. Studies have shown that EXT gene family members have the activities of heparan ... | |||
TMPY-03405 | SPOCK1 Protein, Human, Recombinant (aa 21-429, His) | Human | Baculovirus Insect Cells |
Osteonectin, also known as SPOCK1, is an extracellular heparan/chondroitin sulfate proteoglycan. Members of this family are known as testicans, also called SPOCKs. They are characterized structurally by an N-terminal tes... | |||
TMPJ-01166 | IGFBP-7 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Insulin-like growth factor-binding protein 7(IGFBP-7) is a secreted glycosylated protein that contains three protein domain modules. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase ... | |||
TMPY-01412 | Glypican 5 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Glypican-5 (GPC5), is a cell membrane protein that belongs to the glypican family. The glypicans compose a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans that may play a role in the control... | |||
TMPJ-00330 | GPC1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The Glypicans are a small multigene family of GPI-linked proteoglycans that play a key role in growth factor signaling. Human Glypican 1 (GPC1) is synthesized as a 558 amino acid (aa) preproprecursor that contains a 23 a... | |||
TMPY-05250 | CLEC3A Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
C-type lectin domain family 3 member A (CLEC3A) is a poorly characterized protein belonging to the superfamily of C-type lectins. Elevated CLEC3A expression may correlate with breast IDC metastatic potential and indicate... |