ホーム 計算ツール
代理店ログイン

検索結果

Search Results for " JNJ-1013 "

ターゲット

2

阻害剤

カタログ番号 製品名 別名 ターゲット
T78054 JNJ-1013 Apoptosis
JNJ-1013 is a potent and selective IRAK1 degrader, demonstrating IC50 values of 72 nM for IRAK1, 443 nM for IRAK4, and 1071 nM for VHL FP. It induces apoptosis and augments the expression of cleaved PARP while decreasing...
T77090 Mitazalimab
Mitazalimab (ADC-1013; JNJ-64457107) is an FcγR-dependent CD40 agonist that exhibits directed activity against tumors. By activating antigen-presenting cells, such as dendritic cells (DC), it triggers the initiation of t...