2
1
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T3363L | Jervine HCl | Jervine hydrochloride | |
Jervine is a naturally occurring steroidal alkaloid derived from the Veratrum plant species. Over the Hedgehog signaling pathway, Jervine effectively inhibits tumor growth using three human tumor xenograft models. Jervin... | |||
T31415 | Diacetyljervine | NSC-406352,NSC 406352,N-acetyl-,N,O-Diacetyljervine,Jervine,NSC406352 | |
Diacetyljervine is a bioactive chemical. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T3363 | Jervine | Iervin,11-Ketocyclopamine,Jerwiny | Hedgehog/Smoothened , Smo |
The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signa... |