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TP1895L1 |
KYL acetate(676657-00-4 free base)
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Ephrin Receptor
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KYL acetate is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP... |
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TP1895 |
KYL peptide
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KYL |
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KYL peptide is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP... |
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T40026 |
Pomalidomide 4'-alkylC3-acid
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4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid |
Others
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Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- (4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid) is a Cereblon ligand with alkyl linker and termin... |
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T0604 |
Desalkylterbuthylazine
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Others
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Desalkylterbuthylazine is used as pharmaceutical intermediates. |
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T40030 |
Thalidomide 4'-ether-alkylC2-amine hydrochloride
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halidomide-linker 6 |
E3 Ligase Ligand-Linker Conjugate
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Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate. |
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T84903 |
Pomalidomide 4'-alkylC6-azide
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HUN-55727,HUN55727,HUN 55727,Pomalidomide 4'-alkylC6-azide |
Others
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Pomalidomide 4'-alkylC6-azide, a Pomalidomide-based cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. It is designed to attach to a protein through a linker, enabling the formation of PROTAC [1]. |
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T36276 |
Thalidomide 4'-oxyacetamide-alkylC8-amine
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Thalidomide 4'-oxyacetamide-alkylC8-amine |
Others
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Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functi... |
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T36282 |
VH 032 amide-alkylC7-amine
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VH 032 amide-alkylC7-amine |
Others
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Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of funct... |
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T36250 |
Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine
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Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine |
Others
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Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC1-PEG3-alkylC3 linker with terminal amine ready for conjugation to a target protein ligand. Part of a ra... |
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T84910 |
Lenalidomide 4'-alkyl-C5-azide
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SUN55786,SUN 55786,Lenalidomide 4'-alkylC5-azide,SUN-55786 |
Others
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Lenalidomide 4'-alkyl-C5-azide, a functionalized cerebellar ligand designed for PROTAC development, comprises an E3 ligand and an alkyl LC5 ligand featuring terminal azides for coupling with a target protein ligand [1]. |
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T36270 |
(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride
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VH 032 phenol-alkylC6-amine |
Others
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Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of funct... |
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T39876 |
Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride
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Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride |
Others
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Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride consists of a cereblon (CRBN) ligand for the E3 ubiquitin ligase and a linker, making it suitable for PROTACs design. |
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T70854 |
Protokylol hydrochloride
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Others
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Protokylol hydrochloride is the salt form of Protokylol (free base) (Asmetil, Caytine, Palison, Ventaire), a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States. It is methylenedioxyphe... |
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T35469 |
A 410099.1 amide-alkylC4-amine
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A 410099.1 amide-alkylC4-amine |
Others
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Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionali... |
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T36283 |
VH 032 amide-alkylC8-acid
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VH 032 amide-alkylC8-acid |
Others
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Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC8 linker with terminal carboxylic acid ready for conjugation to a target protein lig... |
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T36281 |
VH 032 amide-alkylC5-amine
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VH 032 amide-alkylC5-amine |
Others
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Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand. Part ... |
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T36280 |
VH 032 amide-alkylC4-acid
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VH 032 amide-alkylC4-acid |
Others
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Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC4 linker with terminal carboxylic acid ready for conjugation to a target protein lig... |
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T36277 |
VH 032 amide-alkylC2-acid
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VH 032 amide-alkylC2-acid |
Others
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Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC2 linker with terminal carboxylic acid ready for conjugation to a target protein lig... |
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T18306 |
MC-Alkyl-Hydrazine Modified MMAF
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Others
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MC-Alkyl-Hydrazine Modified MMAF is a potent antitumor drug-linker conjugate for ADC, incorporating Modified MMAF, a tubulin inhibitor, through a noncleavable MC-Alkyl-Hydrazine linkage[1]. |
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T36278 |
VH 032 amide-alkylC3-acid
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VH 032 amide-alkylC3-acid |
Others
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Functionalized von-Hippel-Lindau protein ligand (VHL) for research and development; incorporates an E3 ligase ligand plus alkylC3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Par... |
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T83961 |
Thalidomide 5'-amine-alkylC6-amine
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Others
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Thalidomide 5'-amine-alkylC6-amine serves as a specialized cereblon ligand for PROTAC research and development, combining an E3 ligase ligand and an alkylC6 linker with a terminal amine for target protein ligand conjugat... |
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T36279 |
VH 032 amide-alkylC3-amine
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VH 032 amide-alkylC3-amine |
Others
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Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl C3 linker and terminal amine ready for conjugation to a target protein ligand. Pa... |
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T36274 |
VH 101 phenol-alkylC6-amine
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VH 101 phenol-alkylC6-amine |
Others
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Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC6 linker with terminal amine ready for conjugation to a target protein ligand. Pa... |
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T36263 |
Pomalidomide 4'-alkylC8-acid
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Pomalidomide 4'-alkylC8-acid |
Others
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Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal acid ready for conjugation to a target protein ligand. Part of a range of functio... |
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T74372 |
N-Desalkyludenafil
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Others
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N-Desalkyludenafil, a metabolite of Udenafil, functions as a PDE5 inhibitor and is utilized in the study of erectile dysfunction [1]. |
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T83954 |
VH 032 amide-alkylC7-acid
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(S,R,S)-AHPC-amido-C7-acid |
Others
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VH 032 amide-alkylC7-acid is a specialized compound designed for PROTAC research and development, serving as a functionalized von-Hippel-Lindau (VHL) protein ligand. It combines an E3 ligase ligand with an alkylC7 linker... |
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T40053 |
Boc-A 410099.1 amide-alkylC4-amine
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Boc-A 410099.1 amide-alkylC4-amine |
Others
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Boc-A 410099.1 amide-alkylC4-amine is a functionalized IAP ligand for PROTACs, comprising of an IAP ligand and an amide-alkylC4 linker terminating in an amine group. It has the ability to form conjugates with target prot... |
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T24670 |
Protokylol
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JB-251,Protokylolum,JB 251,JB251,Protoquilol |
Others
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Protokylol is a β-adrenergic receptor agonist. |
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T36273 |
VH 101 phenol-alkylC4-amine
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VH 101 phenol-alkylC4-amine |
Others
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Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Pa... |
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T34865 |
Thyminalkylamine
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Others
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Thyminalkylamine is a biochemical. |
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T84909 |
Lenalidomide 4'-alkyl-C3-azide
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Others
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Lenalidomide 4'-alkyl-C3-azide (compound 4a), a chemically modified version of the orally active immunomodulator lenalidomide, is engineered for the synthesis of PROTACs. This compound, serving as a ligand for the ubiqui... |
