4
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TMIH-0295 | LBQ657-d4 | ||
LBQ657-d4 is a deuterated compound of LBQ657. LBQ657 has a CAS number of 149709-44-4. Sacubitrilat (LBQ657) is an effective inhibitor of active neprilysin (NEP). | |||
TQ0106 | Sacubitrilat | LBQ-657 | Neprilysin |
Sacubitrilat (LBQ-657) (LBQ657) is an effective inhibitor of active neprilysin (NEP). | |||
T4200 | Sacubitril hemicalcium salt | AHU-377 (hemicalcium salt),AHU377 calcium salt | Neprilysin |
Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug ... | |||
T4574L | Sacubitril sodium | AHU377,AHU-377,LCZ696,AHU 377 | |
Sacubitril is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. |