ホーム 計算ツール
代理店ログイン

検索結果

Search Results for " MINK "

ターゲット

6

阻害剤

カタログ番号 製品名 別名 ターゲット
T8730 BMS986260 TGF-beta/Smad
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).
T69851 Riminkefon
Riminkefon is a kappa opioid receptor agonist .
T0860L Mefloquine Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998 Others
Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic l...
T0860 Mefloquine hydrochloride Mefloquin hydrochloride,Mefloquine HCl Potassium Channel , SARS-CoV , Reactive Oxygen Species , Parasite , Autophagy
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
T36016 PF 06260933 dihydrochloride
MAP4K4 (HGK) inhibitor (IC50 = 140 nM). Also inhibits MINK and TNIK (IC50 values are 8 and 13 nM, respectively). Improves fasting hyperglycemia in mice. Orally active. Ammirati et al (2015) Discovery of an in vivo tool t...
T33945 PF-06260933 HCl PF06260933 dihydrochloride,PF-06260933 dihydrochloride,PF 06260933 dihydrochloride
PF-06260933 Dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM). It can improve the fasting hyperglycemia in mice. In addition, it inhibited Mink and Tnik (IC50 values of 8 and 13 nM, respectively).