|
T14365 |
AZ PFKFB3 26
|
|
Glucokinase
|
|
AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively[1]. AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. |
|
T67874 |
PFKFB3-IN-2
|
|
Glucokinase
|
|
PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. Anti-sense treatment against PFKFB3 was shown to reduce tumor growth rate in vivo. |
|
T26730 |
AZ-PFKFB3-67
|
|
|
|
AZ-PFKFB3-67 is a novel, potent and selective inhibitor of PFKFB3. |
|
T62894 |
AZ-PFKFB3-67 quarterhydrate
|
|
|
|
AZ-PFKFB3-67 quarterhydrate is a selective and potent inhibitor of the metabolic kinase PFKFB3 kinase, acting on PFKFB3 (IC50: 11 nM), PFKFB2 (IC50: 159 nM) and PFKFB1 (IC50: 1130 nM). |
|
T23552 |
YZ9
|
|
Glucokinase
|
|
PFKFB3 inhibitor |
|
T3105 |
PFK-158
|
|
Apoptosis
,
Glucokinase
,
Autophagy
|
|
PFK-158 is an effective and specific inhibitor PFKFB3. |
|
T2455 |
PFK-015
|
PFK15,PFK 015 |
Glucokinase
,
Autophagy
|
|
PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM). |
|
T11741 |
KAN0438757
|
|
Glucokinase
,
Autophagy
|
|
KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM. |
|
T22223 |
3PO
|
|
Glucokinase
,
Autophagy
|
|
3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 μM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 μM). It suppresses glucose uptake, and decrea... |
|
T3260 |
(E)-3PO
|
3PO |
Glucokinase
|
|
(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor. |
|
T40565 |
5MPN
|
|
|
|
5MPN is a novel compound that functions as a highly potent and selective inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4). This compound demonstrates oral activity and serves as a first-in-cla... |
