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T29908 |
Alprostadil ethyl ester
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Prostaglandin E1 ethyl ester,PGE1 ethyl ester |
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Alprostadil ethyl ester is a biochemical used in the treatment of scleroderma. |
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T29907 |
Alprostadil sodium
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PGE1 sodium salt,Prostaglandin E1 sodium |
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Alprostadil sodium is a prostaglandin receptor ligand with Ki values of 36, 10, 1.1, 2.1, and 33 nM for EP1, EP2, EP3, EP4, and IP, respectively, in mice.It induces vasodilatation and inhibits platelet aggregation, and i... |
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T15757 |
Limaprost
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17α,20-dimethyl-δ2-PGE1,OP1206,ONO1206 |
PGE Synthase
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Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood... |
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T36775 |
13,14-dihydro Prostaglandin E1
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13,14-dihydro Prostaglandin E1 |
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13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and wash... |
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T34550 |
SC 31391
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SC31391,SC-31391 |
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SC 31391 is a PGE1 analog. |
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T36726 |
6-keto Prostaglandin E1
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6-keto Prostaglandin E1 |
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6-keto Prostaglandin E1 is a bioactive derivative of PGE1 that plays a role in antiplatelet aggregation and depolymerization. |
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T73346 |
SC 34301
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Enisoprost |
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SC 34301 (Enisoprost), a potent and orally active prostaglandin E1 (PGE1) analog, significantly enhances survival rates and reduces bacterial translocation in burned mice. |
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T36147 |
13,14-dihydro-15-keto Prostaglandin E1
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13,14-dihydro-15-keto Prostaglandin E1 |
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13,14-dihydro-15-keto Prostaglandin E1 inhibits ADP-induced platelet aggregation in human isolated platelet-rich plasma (IC50=14.8 μg/mL) and is a PGE1 metabolite. |
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T36214 |
16,16-dimethyl Prostaglandin E1
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16,16-dimethyl Prostaglandin E1 |
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16,16-dimethyl Prostaglandin E1 is a PGE1 (T1626) analog that induces bronchoconstriction and vascular smooth muscle contraction and inhibits indomethacin-induced cell elongation. |
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T36154 |
15(S)-15-methyl Prostaglandin E2
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15(S)-15-methyl Prostaglandin E2 |
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15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2. It is a potent gastric antisecretory and antiulcer compound. 15(S)-15-methyl PGE2 binds to human myometrium with twice the affinity of PGE2 and is te... |
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T37773 |
Tetranor-PGEM
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tetranor-Prostaglandin E Metabolite,tetranor-PGEM |
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tetranor-PGEM is the major urinary metabolite of PGE1 and PGE2, and is used as a marker of PGE2 biosynthesis.[1],[2] About 15% of an infused dose of PGE2 appears as this metabolite in the urine of humans. Normal healthy ... |
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T36157 |
8-iso Prostaglandin A1
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8-iso Prostaglandin A1 |
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8-iso Prostaglandin A1 (8-iso PGA1) is an isoprostane and a member in a large family of prostanoids of non-cyclooxygenase origin. It occurs as a common minor impurity in most commercial preparations of PGE1. The biologic... |
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T36209 |
15-keto Prostaglandin A1
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15-keto Prostaglandin A1 |
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Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 ... |
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T70865 |
BMY-42393
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BMY-42393 is orally active and selective platelet aggregation inhibitor. BMY-42393 is also a prostacyclin partial agonist that inhibited ADP, collagen and thrombin-induced platelet aggregation (IC50 range 0.3 - 2.0 mic... |
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T37233 |
(±)14(15)-EpEDE
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8,11,14-Eicosatrienoic acid, also known as dihomo-γ-linolenic acid , is a polyunsaturated fatty acid (PUFA) produced from γ-linolenic acid by the action of fatty acid elongases. It can be metabolized by the cyclooxygenas... |
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T36167 |
8-iso-15-keto Prostaglandin F2β
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8-iso-15-keto Prostaglandin F2β |
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8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α of non-enzymatic origin. It is one of 64 possible isomers of PGF2α which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2β exhibits ... |
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T83807 |
Rp-Adenosine-5'-O-(1-thiotriphosphate) sodium
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Rp-ATP-α-S |
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Rp-Adenosine-5'-O-(1-thiotriphosphate) (Rp-ATP-α-S), a sulfur-containing nucleotide derivative isomer and a purinergic P2Y1 receptor agonist, promotes calcium mobilization in HEK293 cells expressing the human P2Y1 recept... |
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T62532 |
MRS2395
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MRS2395 is a dipivaloyl derivative and a potent antagonist of the P2Y12 receptor. MRS2395 inhibited ADP-induced platelet activation (Ki: 3.6 μM). MRS2395 enhances platelet dense granule release in response to TRAP-6. |
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T37441 |
KMN-80
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The prostaglandin E receptor 4 (EP4) is one of four G protein-coupled receptors that mediate the actions of prostaglandin E2 . Binding of PGE2 to the EP4 receptor causes an increase in intracellular cyclic AMP, which pla... |
