Prostaglandin Receptor

Prostaglandin receptors or prostanoid receptors represent a sub-class of cell surface membrane receptors that are regarded as the primary receptors for one or more of the classical, naturally occurring prostanoids viz., prostaglandin D2, , PGE2, PGF2alpha, prostacyclin (PGI2), thromboxane A2 (TXA2), and PGH2.[1] They are named based on the prostanoid to which they preferentially bind and respond, e.g. the receptor responsive to PGI2 at lower concentrations than any other prostanoid is named the Prostacyclin receptor (IP). One exception to this rule is the receptor for thromboxane A2 (TP) which binds and responds to PGH2 and TXA2 equally well.

Cat. No.	製品名	CAS No.	Purity
TN4675	Nortrachelogenin	34444-37-6	98%
TN4675	Nortrachelogenin ((-)-Wikstromol), which can be extracted from Partrinia scabiosaefolia, has antifungal activity and induces membrane disruption and cysteinyl as...
T1978	GW627368	439288-66-1	98%
T1978	GW627368X is a novel, potent and selective antagonist of prostanoid EP4 receptor.
T5150	Treprostinil	81846-19-7	98%
T5150	Treprostinil is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).
T35610	2,5-dimethyl Celecoxib	457639-26-8	98%
T35610	2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1...
T15712	Laropiprant	571170-77-9	98%
T15712	Laropiprant is a potent and selective DP receptor antagonist (Ki: 0.57 nM and 2.95 nM for DP receptor and TP Receptor, respectively).
T9622	MF-766	1050656-06-8	98%
T9622	MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM. It behaves as a full antagonist with an IC50 of 1.4 nM (shifted to 1....
TQ0290	ONO-AE3-208	402473-54-5	98%
TQ0290	ONO-AE3-208 is an EP4 antagonist. It suppresses cell migration, invasion, and metastasis of prostate cancer.
T3965	Fevipiprant	872365-14-5	98%
T3965	Fevipiprant is a selective, potent, reversible competitive CRTh2 antagonist.
T1338	Sucralfate	54182-58-0	98%
T1338	Sucralfate is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers.
T15108	DG-041	861238-35-9	98%
T15108	DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation ...
T4981	Anisotropine Methylbromide	80-50-2	98%
T4981	Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.
T13703	Gestonorone Capronate	1253-28-7	98%
T13703	Gestonorone Capronate is a progesterone used to treat benign prostatic hyperplasia and endometrial cancer.
TN1134	Euscaphic acid	53155-25-2	98%
TN1134	Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 w...
T5171	Treprostinil Sodium	289480-64-4	98%
T5171	Treprostinil is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).
T2538	Bimatoprost	155206-00-1	98%
T2538	Bimatoprost is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular hypertension.
T1626	Prostaglandin E1	745-65-3	98%
T1626	Alprostadil is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that ...
T16280	Nedocromil	69049-73-6	98%
T16280	Nedocromil inhibits the action or formation of multiple mediators. Which including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).
T5841	Travoprost	157283-68-6	98%
T5841	Travoprost is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.
T28958	TG6-129	1164464-14-5	98%
T28958	TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 µM. TG6-129 red...
TQ0025	E7046	1369489-71-3	98%
TQ0025	E7046 is a specific, orally bioavailable EP4 antagonist (IC50: 13.5 nM, Ki: 23.14 nM), exhibiting anti-tumor activities.