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T29106 |
VH032
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VH-032,VH 032 |
Ligand for E3 Ligase
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VH032 commonly used as a precursor to a PROTAC that hijacks VHL as the E3 ubiquitin ligase component.VH032 is a VHL/HIF-1α interaction inhibitor with a KdPROTACs, which can recruit von Hippel-Lindau (VHL) proteins as a l... |
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T17877 |
VH032-cyclopropane-F
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VHL ligand 3,E3 ligase Ligand 19,Phenolic VH101 |
Others
,
Ligand for E3 Ligase
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VH032-cyclopropane-F is a VHL ligand based on VH032. It is able to utilize linkers to ligands of target proteins to yield PROTAC molecules such as PROTAC 1. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4. |
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T18675 |
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride
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VH032 amide-PEG2-amine,VH032-PEG2-NH2 dihydrochloride,VH032-linker 12 |
Others
,
Ligand for E3 Ligase
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(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-linker 12) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker[1]. |
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T41171 |
BODIPY FL VH032
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BODIPY FL VH032 is a high-affinity VHL fluorescent probe (Kd= 3.01 nM) with application in time-resolved fluorescence resonance energy-transfer (TR-FRET) assays for high-throughput identification and characterization of ... |
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T18600 |
VH032 thiol
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VHL ligand 6 |
Others
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VH032 thiol (VHL ligand 6) is a VHL ligand that interacts with pan-BET inhibitor JQ1 through a linker to create a PROTAC[1] compound. |
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T36272 |
VH032-OH
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VH 032, phenol |
Others
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Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand with terminal hydroxyl ready for conjugation to a target protein ligand. Part of a range of fun... |
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T17881 |
(S,R,S)-AHPC-C10-NH2
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VH032-C10-NH2 |
Others
,
Ligand for E3 Ligase
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(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate, comprising the (S,R,S)-AHPC-based VHL ligand and a linker, designed for BET-targeted PROTAC applications. |
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T17230 |
VH032-PEG3-acetylene
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Others
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VH032-PEG3-acetylene is a synthesized conjugate compound consisting of a VH032-based VHL ligand and a linker, designed for use in PROTAC technology as an E3 ligase ligand-linker conjugate[1]. |
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T17927 |
(S,R,S)-AHPC TFA
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VH032-NH2 TFA,VHL ligand 1 TFA |
Others
,
Ligand for E3 Ligase
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(S,R,S)-AHPC TFA (VHL ligand 1 TFA) (VH032-NH2 TFA) is a VH032-based ligand designed for von Hippel-Lindau (VHL) protein recruitment. This compound can be linked to protein ligands (e.g., BCR-ABL1) using a linker to crea... |
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T17996 |
VH032-PEG5-C6-Cl
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HaloPROTAC 2 |
Others
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VH032-PEG5-C6-Cl (HaloPROTAC 2) is a small molecule HaloPROTAC that incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based ass... |
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T8412 |
(S,R,S)-AHPC
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VH032-NH2,MDK7526,VHL ligand 1 |
Others
,
Ligand for E3 Ligase
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(S,R,S)-AHPC (VH032-NH2) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC is potential useful for the targeted degradation of the androgen receptor. |
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T13877 |
(S,S,S)-AHPC hydrochloride
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(S,S,S)-VH032-NH2 hydrochloride |
Ligand for E3 Ligase
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(S,S,S)-AHPC hydrochloride is a von Hippel-Lindau (VHL) aminoblock. (S,S,S)-AHPC (Compound 27) is often used as a negative control for (S,R,S)-AHPC. (S,R,S)-AHPC is a VHL ligand based on VH032 and can be used to recruit ... |
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T18602 |
VH032-thiol-C6-NH2
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VHL Ligand-Linker Conjugates 14,E3 ligase Ligand-Linker Conjugates 29 |
Others
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VH032-thiol-C6-NH2, also known as VHL Ligand-Linker Conjugates 14, is a synthesized compound that functions as an E3 ligase ligand-linker conjugate. This compound combines the VH032 based VHL ligand with a linker commonl... |
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T84747 |
(R,S,S)-VH032
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Others
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(R,S,S)-VH032 is a ligand for E3 ligase and a VHL/HIF-1α interaction inhibitor utilized in the synthesis of PROTACs, particularly the tau-targeting small molecule PROTAC C004019 [1]. As a VHL ligand, it recruits von Hipp... |
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T17921 |
(S,R,S)-AHPC-PEG4-N3
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VH032-PEG4-N3,VHL Ligand-Linker Conjugates 5,E3 ligase Ligand-Linker Conjugates 4 |
Others
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PROTAC Linker
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(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized conjugate that functions as a ligand-linker in E3 ligase-based systems. It is composed of the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, both c... |
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T17920 |
(S,R,S)-AHPC-PEG1-N3
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VHL Ligand-Linker Conjugates 9,VH032-PEG1-N3,E3 ligase Ligand-Linker Conjugates 3 |
Others
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Ligand for E3 Ligase
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(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG1-N3 incorporates the (S,R,S)-AHPC based VHL ligand and 1-unit PEG linker used in PROTAC tec... |
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T15190L |
(S,R,S)-AHPC-PEG4-NH2
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VHL Ligand-Linker Conjugates 4,E3 ligase Ligand-Linker Conjugates 7 Free Base,VH032-PEG4-NH2 |
Others
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Ligand for E3 Ligase
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(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) is a synthetic E3 ligase ligand-linker conjugate comprising a VHL ligand based on (S,R,S)-AHPC and a 4-unit PEG linker. |
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T17909 |
(S,R,S)-AHPC-PEG3-N3
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VHL Ligand-Linker Conjugates 8,VH032-PEG3-N3,E3 ligase Ligand-Linker Conjugates 12 |
Others
,
E3 Ligase Ligand-Linker Conjugate
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Ligand for E3 Ligase
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(S, R, S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) is a synthesized E3 ligase ligand-linker conjugate. (S, R, S)-AHPC-PEG3-N3 incorporates the (S, R, S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC tec... |
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T18640 |
(S,R,S)-AHPC-C4-NH2 hydrochloride
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VH032-C4-NH2 hydrochloride,E3 ligase Ligand-Linker Conjugates 28,VHL Ligand-Linker Conjugates 13 |
Others
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Ligand for E3 Ligase
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(S,R,S)-AHPC-C4-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 28) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker. |
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T77916 |
(S,R,S)-AHPC-Boc
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VH032-Boc |
Others
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(S,R,S)-AHPC-Boc (VH032-Boc) serves as a ligand for the von Hippel-Lindau (VHL) protein recruitment in PROTAC technology [1]. |
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T17925 |
(S,R,S)-AHPC-PEG2-NH2
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VH032-PEG2-NH2,VHL Ligand-Linker Conjugates 3,E3 ligase Ligand-Linker Conjugates 6 Free Base |
Others
,
E3 Ligase Ligand-Linker Conjugate
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(S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis ... |
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T17922 |
(S,R,S)-AHPC-PEG3-NH2 hydrochloride
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VHL Ligand-Linker Conjugates 1 hydrochloride,E3 ligase Ligand-Linker Conjugates 5,VH032-PEG3-NH2 hydrochloride,VHL Ligand-Linker Conjugates 1 HCl |
Others
,
E3 Ligase Ligand-Linker Conjugate
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(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC-based VHL ligand and 3-unit PEG linker. |
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T17924 |
(S,R,S)-AHPC-PEG2-NH2 hydrochloride
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VH032-PEG2-NH2 hydrochloride,VHL Ligand-Linker Conjugates 3 hydrochloride,E3 ligase Ligand-Linker Conjugates 6 |
Others
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E3 Ligase Ligand-Linker Conjugate
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(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 hydrochloride incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit... |
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T18661 |
(S,R,S)-AHPC-C10-NH2 dihydrochloride
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VH032-C10-NH2 dihydrochloride,VH032-linker 10,VH032 amide-alkylC10-amine |
Others
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Ligand for E3 Ligase
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(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker[1]. |
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T18667 |
(S,R,S)-AHPC-C5-COOH
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VH032-C5-COOH |
Others
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(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized conjugate designed for E3 ligase ligand-linker applications, combining the VH032 VHL-based ligand with a linker for PROTAC development. VH-032 acts as a selective and... |
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T18664 |
(S,R,S)-AHPC-C3-NH2
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VH032-C3-NH2 |
Others
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(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate consisting of an E3 ligase ligand-linker and the VH032 based VHL ligand, which is commonly used in PROTAC technology. This compound serves as a key component ... |
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T13876 |
(S,R,S)-AHPC-propargyl
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VHL ligand 7,VH032-propargyl |
Others
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(S,R,S)-AHPC-propargyl is a VHL ligand which is used in "click reaction" for PROTACs. |
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T18666 |
(S,R,S)-AHPC-C4-NH2
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VH032-C4-NH2 |
Others
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(S,R,S)-AHPC-C4-NH2 is a custom-synthesized conjugate of an E3 ligase ligand-linker, which combines the VHL ligand based on (S,R,S)-AHPC and a linker specifically designed for EED-Targeted PROTAC[1]. |
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T18665 |
(S,R,S)-AHPC-C4-NH2 dihydrochloride
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VH032-C4-NH2 dihydrochloride |
Others
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(S,R,S)-AHPC-C4-NH2 dihydrochloride is a chemically derived E3 ligase ligand-linker conjugate, consisting of the (S,R,S)-AHPC VHL ligand and a linker specifically designed for EED-Targeted PROTAC[1]. |
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T18662 |
(S,R,S)-AHPC-C2-PEG4-N3
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VH032-C2-PEG4-N3 |
Others
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(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate combining the (S,R,S)-AHPC-based VHL ligand with a 4-unit polyethylene glycol (PEG) linker, employed in PROteolysis TAgeting C... |
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T18673 |
(S,R,S)-AHPC-O-Ph-PEG1-NH2
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VH032-O-Ph-PEG1-NH2 |
Others
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(S,R,S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) serves as an E3 ligase ligand-linker conjugate, integrating a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is utilized in PROTAC EED degrader-... |
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T18672 |
(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc
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VH032-O-Ph-PEG1-NH-Boc |
Others
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(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is an E3 ligase ligand-linker conjugate, specifically designed for targeting the EED protein in PROTAC applications[1]. |
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T39735 |
(S,R,S)-AHPC-PEG1-NH2
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VH032-PEG1-NH2,(S,R,S)-AHPC-PEG1-NH2 |
Others
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(S,R,S)-AHPC-PEG1-NH2 (VH032-PEG1-NH2) is a synthesized conjugate combining the VH032-based VHL ligand with a linker designed for use in PROTAC technology, serving as an E3 ligase ligand-linker. |
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T39873 |
(S,R,S)-AHPC-C8-NH2
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VH032-C8-NH2,(S,R,S)-AHPC-C8-NH2 |
Others
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(S, R, S)-AHPC-C8-NH2 (VH032-C8-NH2) is an E3 ligase ligand-linker conjugate. This compound comprises the VH032-based VHL ligand and a linker, specifically designed for AKT PROTAC degrader applications. |
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T39838 |
(S,R,S)-AHPC-C7-amine
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VH032-C7-amine,(S,R,S)-AHPC-C7-amine |
Others
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(S,R,S)-AHPC-C7-amine, also known as VH032-C7-amine, is a chemically synthesized conjugate that functions as an E3 ligase ligand-linker. This compound combines the VH032-based VHL ligand with a specific linker designed f... |
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T39651 |
(S,R,S)-AHPC-C5-NH2
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(S,R,S)-AHPC-C5-NH2,VH032-C5-NH2 |
Others
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(S,R,S)-AHPC-C5-NH2, also known as VH032-C5-NH2, is a synthetic compound designed as an E3 ligase ligand-linker conjugate. This compound combines the VH032-based von Hippel-Lindau (VHL) ligand with a linker, enabling it ... |
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T39872 |
(S,R,S)-AHPC-C6-NH2 dihydrochloride
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(S,R,S)-AHPC-C6-NH2 dihydrochloride,VH032-C6-NH2 dihydrochloride |
Others
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(S, R, S)-AHPC-C6-NH2 dihydrochloride (also known as VH032-C6-NH2 dihydrochloride) is a synthesized compound that functions as a ligand-linker conjugate for E3 ligase. It incorporates the VH032-based VHL ligand along wit... |
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T39931 |
(S,R,S)-AHPC-C8-NH2 hydrochloride
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(S,R,S)-AHPC-C8-NH2 hydrochloride,VH032-C8-NH2 hydrochloride |
Others
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'(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) hydrochloride is a synthetic E3 ligase ligand-linker conjugate, consisting of the VH032-based VHL ligand and a linker for use in PROTAC technology.' |
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T39898 |
(S,R,S)-AHPC-C6-NH2 hydrochloride
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(S,R,S)-AHPC-C6-NH2 hydrochloride,VH032-C6-NH2 hydrochloride |
Others
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(S, R, S)-AHPC-C6-NH2 hydrochloride (also known as VH032-C6-NH2 hydrochloride) is a synthetic E3 ligase ligand-linker conjugate. It combines the VH032-based VHL ligand with a linker designed for AKT PROTAC degrader appli... |
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T39659 |
(S,R,S)-AHPC-CO-C9-acid
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VH032-NH-CO-C9-acid,(S,R,S)-AHPC-CO-C9-acid |
Others
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(S,R,S)-AHPC-CO-C9-acid is a ligand-linker conjugate specifically designed to function as an E3 ligase ligand. This compound possesses the capability to be attached to a ligand, which enables the formation of PROTACs wit... |
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T18872 |
(S,R,S)-AHPC-PEG5-COOH
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VH032-PEG5-COOH,E3 Ligase Ligand-Linker Conjugates 58,VHL Ligand-Linker Conjugates 16 |
Others
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(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for use in PROTAC technology. It consists of the (S,R,S)-AHPC based VHL ligand and a 5-unit PEG linker [1]. |
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T17905 |
(S,R,S)-AHPC-PEG1-OTs
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VH032-PEG1-OTs,VHL Ligand-Linker Conjugates 2,E3 ligase Ligand-Linker Conjugates 51 |
Others
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(S,R,S)-AHPC-PEG1-OTs is a chemically synthesized conjugate, functioning as an ligase ligand-linker for E3 ligase. It incorporates the VHL ligand derived from (S,R,S)-AHPC and a 1-unit PEG linker. This synthesized compou... |
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T18663 |
(S,R,S)-AHPC-C3-NH2 TFA (2361119-88-0 free base)
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(S,R,S)-AHPC-C3-NH2 TFA,VH032-C3-NH2 TFA |
Others
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(S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the sy... |
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T17913 |
(S,R,S)-AHPC-PEG2-N3
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VHL Ligand-Linker Conjugates 6,VH032-PEG2-N3,E3 ligase Ligand-Linker Conjugates 13 |
Others
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Ligand for E3 Ligase
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(S,R,S)-AHPC-PEG2-N3 (VHL Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate containing a (S,R,S)-AHPC based VHL ligand and 2 unit PEG linker. |
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T17910 |
(S,R,S)-AHPC-PEG2-C4-Cl
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E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl |
Others
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(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-bas... |
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T17926 |
(S,R,S)-AHPC-PEG6-C4-Cl
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VHL Ligand-Linker Conjugates 10,E3 ligase Ligand-Linker Conjugates 9,VH032-PEG6-C4-Cl |
Others
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(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-bas... |
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T17923 |
(S,R,S)-AHPC-PEG3-NH2
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E3 ligase Ligand-Linker Conjugates 5 Free Base,VH032-PEG3-NH2,VHL Ligand-Linker Conjugates 1 |
Others
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(S,R,S)-AHPC-PEG3-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, incorporating the (S,R,S)-AHPC VHL ligand and a 3-unit PEG linker, which are utilized in PROTAC technology. |
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T15190 |
(S,R,S)-AHPC-PEG4-NH2 hydrochloride
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E3 ligase Ligand-Linker Conjugates 7,VH032-PEG4-NH2 hydrochloride,VHL Ligand-Linker Conjugates 4 hydrochloride |
Others
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(S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically ... |
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T17911 |
(S,R,S)-AHPC-C6-PEG3-C4-Cl
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VH032-C6-PEG3-C4-Cl,VHL Ligand-Linker Conjugates 12,E3 ligase Ligand-Linker Conjugates 8 |
Others
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(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in ce... |
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T39494 |
(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH
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VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH,(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH |
Others
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(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, also known as VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, is a conjugate compound comprising a ligand-linker that targets E3 ligase and, on one end, features a... |
