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T12148 |
N-Desmethyltamoxifen hydrochloride
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Estrogen Receptor/ERR
,
Endogenous Metabolite
,
PKC
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N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans. |
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T60115 |
EM-651
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2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)- |
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EM-651 (2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-) is an enantiomer of EM-652, IC50=20.0 nM. EM-652 is an orally active pure antiestrogen and selective estrogen rece... |
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T23273 |
RU 58668
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|
Others
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Pure antiestrogen that downregulates estrogen receptor expression |
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T26295 |
Trioxifene mesylate
|
LY 133314,LY-133314,LY133314 |
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Trioxifene mesylate is an antiestrogen that suppresses growth hormone secretion. |
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T23737 |
Anordiol
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H 241,H241,AF-45,AF 45,AF45 |
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Anordiol is an antiestrogen with estrogenic activity. It also is known to inhibit fertility. |
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T25262 |
Clometherone
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Lilly 38000,Lilly38000,Clometeron,Lilly-38000 |
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Clometherone is a synthetic pregnane steroid and derivative of progesterone which is used as an antiestrogen and antiandrogen. |
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T12312 |
OP-1074
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Estrogen/progestogen Receptor
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OP-1074 is a pure antiestrogen and a selective degrader of ER, shows specific antiestrogenic activity for ERα and ERβ. |
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T15452 |
GW7604
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Others
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GW7604 is an antiestrogen and it also is the metabolite of GW5638. GW5638 is an antagonist of high-affinity estrogen receptor (ER). |
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T40166 |
Bexirestrant
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Bexirestrant is an orally active ER-α degrader commonly employed in the research of antiestrogen and antineoplastic therapies. |
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T72945 |
Palazestrant
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|
|
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Palazestrant, an antiestrogen and antineoplastic agent, effectively targets ER+/HER2+ cancer when used in conjunction with a HER2 inhibitor. |
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T70013 |
Pipendoxifene
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|
|
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Pipendoxifene, also known as ERA-923, is a new antiestrogen with potential anticancer activity. ERA-923 potently inhibits estrogen binding to ER-alpha (IC50 = 14 nM). In ER-alpha-positive human MCF-7 breast carcinoma cel... |
