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TP2032 |
Des-Gln14-Ghrelin
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des-Gln14-Ghrelin (rat) |
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An endogenous ligand for the ghrelin receptor (GHS-R1a), produced by alternative splicing of the rat ghrelin gene. Potently induces Ca2+ release in cells expressing ghrelin receptors (EC50 = 2.4 nM) and stimulates GH rel... |
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T40234 |
Ghrelin receptor full agonist-2
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Others
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Ghrelin receptor full agonist-2 is a highly potent Ghrelin receptor full agonist. |
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TP2241 |
[Des-octanoyl]-Ghrelin (human)
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Others
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[Des-octanoyl]-Ghrelin (human) is a Non-acylated, major circulating isoform of ghrelin. |
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TP2242 |
[Des-octanoyl]-Ghrelin (rat)
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Others
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[Des-octanoyl]-Ghrelin (rat) is a Non-acylated, major circulating isoform of ghrelin. |
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T75928 |
Des-Gln14-Ghrelin TFA
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Des-Gln14-Ghrelin TFA serves as a potent endogenous ligand for the growth hormone secretagogue receptor, effectively inducing increases in intracellular calcium levels ([Ca2+]i) in CHO-GHSR62 cells with an EC50 of 2.4 nM... |
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T10319 |
Anamorelin
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RC-1291,ONO-7643 |
GHSR
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Anamorelin (ONO-7643) is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay). |
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T16508 |
PF-5190457
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PF-05190457 |
GHSR
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PF-5190457 is an effective and selective ghrelin receptor inverse agonist (pKi: 8.36). |
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T7225 |
AnaMorelin hydrochloride
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RC-1291 hydrochloride,ONO-7643 hydrochloride |
GHSR
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AnaMorelin hydrochloride (RC-1291 hydrochloride) is a novel ghrelin receptor agonist(EC50 : 0.74 nM, in the FLIPR assay). |
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T23543 |
YIL 781
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GHSR
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YIL 781 is a selective ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM), showing a weak affinity for kinesin receptors (K = 6 μM). YIL 781 improves glucose homeostasis in vivo and in vitro by blocking ghrelin secretion... |
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TP1931L1 |
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate
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[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base) |
cholecystokinin
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[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist ... |
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T10319L |
Anamorelin Fumarate
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ONO-7643 Fumarate,RC1291 Fumarate |
Others
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T22898 |
L-692585
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L-692,585 |
Others
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ghrelin receptor (GHS-R1a) agonist |
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T34281 |
Relamorelin
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BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131 |
GHSR
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Relamorelin (RM-131), a selective and potent growth hormone-releasing peptide/growth hormone secretagogue receptor (GHSR) agonist, is a potent growth hormone-releasing peptide mimetic with a high affinity for the GHS-1a ... |
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T27443 |
GSK 894281
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GSK894281,GSK-894281 |
Others
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GSK 894281 is a ghrelin receptor agonist. It may produces myocardial degeneration/necrosis in rats. |
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T23413 |
Tabimorelin hemifumarate
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Others
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orally active ghrelin receptor (GHS-R1a) agonist |
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T27451 |
GSK1614343
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GSK-1614343,GSK 1614343 |
Others
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GSK1614343 is an antagonist of ghrelin receptor. |
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T27493 |
GSK-894490A
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GSK 894490A |
Others
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GSK-894490A is an agonist of ghrelin receptor. GSK-894490A crosses the blood/brain barrier and elicit pro-cognitive effects. |
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T29174 |
YIL781 hydrochloride
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YIL 781,YIL-781,YIL781 HCl,YIL781 |
Others
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YIL781 is a ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM) with no significant affinity for the motilin receptor (Ki = 6 μM). |
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T28812 |
SM-130686
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SM 130686,SM130,686,SM 130,686 |
Others
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SM-130,686 is a potent, orally-active agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and growth hormone secretagogue. It has around half the potency of the endogenous agonist ghrelin as a stimulator o... |
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TP1894 |
K-(D-1-Nal)-FwLL-NH2
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High affinity and potent ghrelin receptor inverse agonist (Ki values are 4.9 and 31 nM in COS7 and HEK293T cells, respectively). Blocks ghrelin receptor-mediated Gq- and G13-dependent signaling pathways. |
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TP2236 |
Cortistatin-8
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Others
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ghrelin receptor antagonist |
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T17202 |
Ulimorelin
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TZP-101 |
Others
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Ulimorelin is a ghrelin receptor agonist (EC50: 29 nM and a Ki of 16 nM). Ulimorelin is a prokinetic agent and causes vasorelaxation through competitive antagonist action at α1-adrenoceptors. |
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T75948 |
K-(D-1-Nal)-FwLL-NH2 TFA
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K-(D-1-Nal)-FwLL-NH2 TFA is a potent and high-affinity inverse agonist of the ghrelin receptor, exhibiting Ki values of 4.9 nM in COS7 cells and 31 nM in HEK293T cells. This compound effectively inhibits ghrelin receptor... |
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T71632 |
TZP-102
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Others
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TZP-102 is a potent, oral, ghrelin receptor agonist that has been shown to improve diabetic gastroparesis symptoms. |
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TP1931 |
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
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Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradyki... |
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T11448 |
GOAT-IN-1
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Others
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TP1439 |
AZP-531
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Azp-531 is a disacylated ghrelin used to improve blood sugar control and weight loss. |
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T82961 |
ASB20123
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ASB20123, a CNP/ghrelin chimeric peptide, promotes bone growth and has potential research applications in growth disorders and dwarfism [1]. |
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T81625 |
Obestatin(human) TFA
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Obestatin(human) TFA, an endogenous peptide originating from the same prepropeptide as ghrelin, is known to suppress food intake and reduce weight gain in rats. |
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T28366 |
PF-04628935
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PF 04628935,PF 4628935,PF4628935,PF04628935,PF-4628935 |
Others
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PF-04628935 is a potent antagonist/inverse agonist of the ghrelin receptor, growth hormone secretagogue receptor 1a (GHS-R1a) with an IC50 of 4.6 nM. PF-04628935 is orally bioavailable and brain penetrant. |
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T39236 |
Relamorelin acetate
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Relamorelin acetate,RM-131 acetate,BIM-28131acetate |
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Relamorelin (RM-131) acetate is a pentapeptide ghrelin analog that acts as a selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR). It exhibits a high affinity for the GHS-1a receptor, with a Ki v... |
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T35787 |
Obestatin (human) (trifluoroacetate salt)
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Obestatin is a 23 amino acid peptide hormone with a conserved C-terminal glycine residue and amidation site that is formed by cleavage of the ghrelin and obestatin prepropeptide.1It binds to the orphan receptor GPR39 (Kd... |
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T35793 |
JMV3002
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JMV3002 |
Others
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Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrel... |
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T81287 |
RFRP-3 (rat)
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RFRP-3 (rat), a neuropeptide, suppresses gonadotropin release and consequently elevates ghrelin mRNA and circulating growth hormone concentrations [1]. |
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T75262 |
Relamorelin TFA
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Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, acts as a potent and selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR), with a K_i of 0.42 nM for the GHS-1a receptor. This compound is... |
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T37412 |
AZ-GHS-22
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Others
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AZ-GHS-22 is an inverse agonist of the growth hormone secretagogue receptor 1a (GHS-R1a), which is also known as the ghrelin receptor.1It binds to GHS-R1a with an IC50value of 0.77 nM. AZ-GHS-22 decreases food intake in ... |
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T75901 |
Obestatin(rat) TFA
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Others
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Obestatin(rat) TFA is a cpeptide derived from the Ghrelin gene, consisting of 23 amino acids. This compound modulates physiological processes by suppressing food intake, inhibiting jejunal contraction, and reducing body-... |
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T68276 |
Macimorelin acetate
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EP-1572 acetate ; AEZS-130 acetate,AEZS-130 acetate,EP-1572 acetate |
Others
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Macimorelin Acetate (EP-1572), an orally active growth hormone (GH) secretagogue and a ghrelin receptor (GHSR) agonist, stimulates GH release. It is utilized in research focusing on adult growth hormone deficiency (AGHD)... |
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TP2215 |
Agouti-related Protein (AGRP) (25-82), human
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Others
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Agouti-related peptide (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It is only synthesized in NPY containing cell bodies located in the ventromedial part of the arcuate nucleus in the hypothalam... |
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T64475 |
FMOC-L-THR
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Others
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FMOC-L-THR (AZP-531) is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight. The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine ... |
