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T19080 |
DOPE
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Others
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DOPE (DOPE) is a neutral helper lipid for cationic liposomes.It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery. |
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T11086 |
DOTAP chloride
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1,2-Dioleoyl-3-trimethylammonium-propane chloride |
Others
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DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) is a useful and effective cationic lipid transfection DNA(plasmids, BacMIDs) and modified nucleic acids (antisense oligonucleotides) without the use of a... |
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T12598 |
Pz-1
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VEGFR
,
c-RET
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T8902 |
DOTMA
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Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride,N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium |
Others
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DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) is a tetra-methylated DOTA analogue. DOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in lipos... |
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TP2505L |
LAH4 acetate
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KKALLALALHHLAHLALHLALALKKA acetate,LAH4 acetate(184776-51-0 Free base) |
Antibacterial
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LAH4 acetate is the α-helical structure of the designed amphoteric peptide antibiotic, which is capable of complexing DNA, associating with the cell surface membrane and wrapped in the endosome, which is destroyed with t... |
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T10823 |
Trans-Pralsetinib
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cis-Pralsetinib,cis-BLU-667 |
c-RET
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trans-Pralsetinib (trans-BLU-667) is an inhibitor of rearranged during transfection (RET). |
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T32780 |
Lipofectin
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Others
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Lipofectin is used to promote the transfection of plasmid vectors in vitro and in vivo. |
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T84758 |
GL67
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N4-Spermine cholesteryl carbamate |
Others
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GL67 (N4-Spermine cholesteryl carbamate), a cationic lipid, facilitates the delivery of nucleic acid agents and vaccines, and is effective in gene transfection [1]. |
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T84756 |
C14-4
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C14-494 |
Others
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C14-4, an ionizable lipid utilized in lipid nanoparticles (LNPs) formulation, has been recognized for its efficacy in transfection and minimal cytotoxicity. |
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T84665 |
Dioleyldimethylammonium chloride
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DODAC |
Others
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Dioleyldimethylammonium chloride (DODAC) is a cationic lipid utilized as a transfection reagent [1]. |
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T74239 |
DOSPA
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Others
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DOSPA, a cationic lipid, exhibits significant potential when formulated with DNA as a transfection system [1]. |
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T84805 |
3-Azidopropylamine
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Others
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3-Azidopropylamine, a click chemistry reagent characterized by its azide group, facilitates the complexation and transfection of plasmid DNA by reacting with the starch sugar present in potato starch [1]. |
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T84666 |
RCB-02-4-8
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Others
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RCB-02-4-8, an ionizable cationic lipid designed for the formulation of lipid nanoparticles (LNPs), enhances mRNA delivery with proven effectiveness in increasing lung transfection efficiency in mice [1]. |
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T39313 |
KALA
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KALA, an amphiphilic peptide, adopts an α-helical conformation under physiological pH conditions. It functions as a fusogenic peptide, modifying the liposomal membrane that encapsulates plasmid DNA, thereby facilitating ... |
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T63358 |
RET-IN-15
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Others
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RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research. |
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T1656L |
Vandetanib Fumarate
|
HSDB 8198,Zactima,Caprelsa,ZD 6474,Vandetanib |
Others
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Vandetanib Fumarate is an orally available tyrosine kinase inhibitor. Vandetanib Fumarate works by blocking RET (REarranged during Transfection), vascular endothelial growth factor receptor (VEGFR-2, VEGFR-3), and epider... |
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TP1811 |
LAH4
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The a-helix of the amphipathic peptide antibiotic LAH4 (KKALLALALHHLAHLALHLALALKKA-NH2) strongly interacts with phospholipid membranes, demonstrating in vitro transfection efficiencies comparable to those of commercially... |
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T63230 |
RET-IN-8
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Others
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RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research. |
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T82398 |
Firefly Luciferase circRNA
|
|
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Firefly Luciferase circRNA, originally isolated from Photinus pyralis (Firefly), expresses a luciferase protein and serves as an optimal marker for monitoring and optimizing transfection efficiency; it is also recommende... |
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T84668 |
DORI
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1,2-Dioleoyl-3-dimethyl-hydroxyethylammonium bromide |
Others
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DORI, a cationic lipid, efficiently delivers plasmid DNA in vitro, exhibiting lower cytotoxicity and high transfection efficiency [1]. |
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T36368 |
2H-Cho-Arg (trifluoroacetate salt)
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|
Others
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2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. It forms a complex with plasmid DNA (pDNA) and dec... |
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T75762 |
LAH4 TFA
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|
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LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, demonstrates potent antimicrobial, nucleic acid transfection, and cell penetration capabilities, alongside high plasmid DNA delivery capacities. It... |
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T84660 |
DSTAP chloride
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CDESA |
Others
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DSTAP chloride (CDESA), a cationic lipid, is utilized in the formation of lipid nanoparticles (LNPs) and exhibits high transfection efficiency [1]. |
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T74752 |
AA-T3A-C12
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Others
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AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts [1] . |
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T74314 |
14:1 EPC trifluoromethanesulfonate
|
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Others
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14:1 EPC trifluoromethanesulfonate, an ethyl-phosphatidylcholine (EPC) derivative with monounsaturated 14:1 chains, exhibits transfection activity. This compound is utilized for drug delivery [1] [2]. |
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T37534 |
DMPAC-Chol
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Others
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DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degrada... |
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T74470 |
3'Ome-m7GpppAmpG ammonium
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Others
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3'Ome-m7GpppAmpG ammonium, a trinucleotide Cap analogue with a locked nucleic acid (LNA) component, demonstrates substantial translational efficiency. It emerges as a promising tool in molecular biology, applicable in mR... |
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T74469 |
3'Ome-m7GpppAmpG
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Others
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3'Ome-m7GpppAmpG, a trinucleotide cap analogue with a locked nucleic acid (LNA) molecule, demonstrates notable translational efficiency. It serves as a promising tool in molecular biology, applicable in mRNA vaccines and... |
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T71576 |
SIM010603
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Others
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SIM010603 is a structurally novel, oral, multi-targeted receptor tyrosine kinase inhibitor. SIM010603 inhibited stem cell factor receptor (Kit), vascular endothelial growth factor receptor-2 (VEGFR-2), platelet-derived g... |
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T37391 |
PSEM 308 hydrochloride
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Others
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PSAM (pharmacologically selective actuator module) agonist. Activates PSAML141F-GlyR chimeric ion channels. Inhibits activity of neurons expressing PSAML141F-GlyR in vivo and activates locus coeruleus noradrenergic neuro... |
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T36350 |
Cho-Arg (trifluoroacetate salt)
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Others
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Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assa... |
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T36359 |
Dios-Arg (trifluoroacetate salt)
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Others
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Dios-Arg is a steroid-based cationic lipid that contains a diosgenin skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay... |
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T82497 |
EGFP circRNA
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eGFP circRNA, originally isolated from the jellyfish Aequorea victoria, is a reporter widely utilized for direct detection in mammalian cell culture due to its bright green fluorescence with an emission peak at 509 nm. I... |
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T35582 |
H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt)
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Others
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H-Arg-Gly-Asp-Cys-OH is a tetrapeptide that contains the arginine-glycine-aspartate (RGD) motif, a sequence that acts as a recognition site for various adhesion proteins.1It inhibits the binding of fibrinogen to endothel... |
