| T4554 |
AG 1406
|
71308-34-4
|
98%
|
|
|
AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.
|
| T1895 |
SKLB 610
|
1125780-41-7
|
98%
|
|
|
SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively, a...
|
| T21593 |
AAL-993
|
269390-77-4
|
98%
|
|
|
AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on oth...
|
| T10531 |
BGB-102
|
807640-87-5
|
98%
|
|
|
BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3, which may be useful in the study of macular deg...
|
| T9904 |
Bevacizumab
|
216974-75-3
|
98%
|
|
|
Bevacizumab, a humanized monoclonal antibody, specifically and with high affinity binds to all isoforms of VEGF-A.
|
| TN1567 |
Delphinidin chloride
|
528-53-0
|
98%
|
|
|
Delphinidin chloride, a natural plant pigment found in berries and red wine, is a precursor of certain anthocyanins. Delphinidin chloride induces the release of ...
|
| T4026 |
SU5408
|
15966-93-5
|
98%
|
|
|
SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.
|
| T76866 |
Icrucumab
|
1024603-92-6
|
98%
|
|
|
Icrucumab ( IMC-18F1) is a humanized IgG1 monoclonal antibody targeting vascular endothelial growth factor receptor-1.Icrucumab has antitumor activity.Icrucumab ...
|
| T76756 |
Parsatuzumab
|
1312797-14-0
|
98%
|
|
|
Parsatuzumab (RG 7414) is a humanized monoclonal antibody targeting EGFL7, which is also used as an immunomodulator.Parsatuzumab selectively inhibits the interac...
|
| T75163 |
GW297361
|
388627-21-2
|
98%
|
|
|
GW297361 is a potent inhibitor of the cell cycle protein-dependent kinase Cdk1 and also inhibits the Pho85 signaling pathway.The IC50s of GW297361 on yeast Cdk1 ...
|
| T9979 |
VEGFR-2-IN-29
|
62802-77-1
|
98%
|
|
|
VEGFR-2-IN-29 is a VEGFR2 inhibitor.
|
| T6154 |
SU11274
|
658084-23-2
|
98%
|
|
|
SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.
|
| TC0036 |
Compound Lup-20(29)-en-3-yl acetate
|
TC0036
|
98%
|
|
|
Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.
|
| T3569 |
SU5214
|
186611-04-1
|
98%
|
|
|
SU5214 is a modulator of tyrosine kinase signal transduction.
|
| T6036 |
Brivanib
|
649735-46-6
|
98%
|
|
|
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR...
|
| T37078 |
VEGFR-2-IN-6
|
444731-47-9
|
98%
|
|
|
VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].
|
| T13156L |
TG 100572 Hydrochloride
|
867331-64-4
|
98%
|
|
|
TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1...
|
| T1948 |
AZD4547
|
1035270-39-3
|
98%
|
|
|
AZD4547, a new-type specific FGFR inhibitor, targets for FGFR1/2/3 (IC50: 0.2/2.5/1.8 nM in cell-free assays).
|
| T21334 |
Bucillamine
|
65002-17-7
|
98%
|
|
|
Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF. Bucillamine is an orally act...
|
| T9929 |
Ramucirumab
|
947687-13-0
|
98%
|
|
|
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
|
