ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T4608 | PDM2 | 688348-25-6 | 98% |
|
| PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist. | ||||
| T20625 | Prochloraz | 67747-09-5 | 98% |
|
| Prochloraz, a broad-spectrum contact imidazole fungicide, is used against several diseases in wheat, barley, and oleaginous plants but also for the treatment of ... | ||||
| T4644 | Tapinarof | 79338-84-4 | 98% |
|
| Tapinarof is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease. | ||||
| TN1451 | Brevifolincarboxylic acid | 18490-95-4 | 98% |
|
| Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarb... | ||||
| T10007 | 1,4-Chrysenequinone | 100900-16-1 | 98% |
|
| 1,4-Chrysenequinone acts as an activator of aryl hydrocarbon receptor (AhR). | ||||
| T5541 | PDM11 | 1032508-03-4 | 98% |
|
| PDM 11 is an antagonist of aryl hydrocarbon receptor (AhR) | ||||
| T4607 | CAY 10465 | 688348-33-6 | 98% |
|
| CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM). | ||||
| T23151 | Phortress | 328087-38-3 | 98% |
|
| Phortress is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor activity. | ||||
| T10938 | D-Kynurenine | 13441-51-5 | 98% |
|
| D-Kynurenine is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D... | ||||
| T7202 | ITE | 448906-42-1 | 98% |
|
| ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity. | ||||
| T5622 | BAY-218 | 2162982-11-6 | 98% |
|
| AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line. | ||||
| T1960 | YL-109 | 36341-25-0 | 98% |
|
| YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo. | ||||
| T1046 | Mexiletine hydrochloride | 5370-01-4 | 98% |
|
| Mexiletine Hydrochloride is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine. ... | ||||
| T2448 | CH-223191 | 301326-22-7 | 98% |
|
| CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR). | ||||
| T0343 | Nimodipine | 66085-59-4 | 98% |
|
| Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells. | ||||
| T9822 | WAY-605471 | 378223-81-5 | 98% |
|
| WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM. | ||||
| T1831 | StemRegenin 1 | 1227633-49-9 | 98% |
|
| StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor. | ||||
| T5281 | Skatole | 83-34-1 | 98% |
|
| Skatole is produced by intestinal bacteria. Skatole regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38. | ||||
| T4938 | Potassium 1H-indol-3-yl sulfate | 2642-37-7 | 98% |
|
| Potassium 1H-indol-3-yl sulfate is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) has recently emerged as a pat... | ||||
| T1159 | Leflunomide | 75706-12-6 | 98% |
|
| Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. | ||||
