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COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as prostaglandin G/H synthase.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T1720 Amfenac Sodium Hydrate 61618-27-7 98%
Amfenac Sodium Hydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety.
T11761 Tarlox-TKI 2135696-72-7 98%
Kinase inhibitor-1 is a kinase inhibitor.
TN3694 Coniferaldehyde 20649-42-7 98%
Coniferaldehyde can significantly inhibit the growth of viability of strains of Oenococcus oeni. Coniferaldehyde exerts anti-inflammatory properties by inducing ...
T3779 Crocin II 55750-84-0 98%
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect ...
TN2079 (-)-Pinoresinol 81446-29-9 98%
(-)-Pinoresinol is isolated from the whole plant of Serissa japonica (Thunb.) Thunb.
T19679 Benoxaprofen 51234-28-7 98%
Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.
T77433 Feladilimab 2252518-85-5 98%
Feladilimab
Feladilimab (GSK3359609) is an IgG4 monoclonal antibody that is an ICOS agonist. Feladilimab binds to ICOS-expressing T cells, induces IFNγ, and increases PD-1/L...
T1191L Metamizole sodium 68-89-3 98%
Metamizole sodium (Analgin) is a drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE.
T60053 Hamaline 2411677-02-4 98%
Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) is a substrate-selective cyclooxygenase-2 (COX-2) inhibitor.
T76760 Sifalimumab 1006877-41-3 98%
Sifalimumab
Sifalimumab (MEDI-545) is a monoclonal antibody that targets IFNα and suppresses abnormal immune activity by binding to interferon-alpha.Sifalimumab is used for ...
T76742 Emapalumab 1709815-23-5 98%
Emapalumab
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface rec...
T76717 Serplulimab 2231029-82-4 98%
Serplulimab (HLX 10) is a humanized monoclonal anti-antibody to PD-1. Serplulimab has antitumor activity and can be used in small cell lung cancer and esophageal...
TN1308 6-Hydroxyflavanone 4250-77-5 98%
6-Hydroxyflavanone, extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxygenase-2 (COX...
TN1143 1-O-Acetyl britannilactone 681457-46-5 98%
1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR...
TC0036 Compound Lup-20(29)-en-3-yl acetate TC0036 98%
Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.
TN4583 Moringin 73255-40-0 98%
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moring...
T19672 Amtolmetin guacil 87344-06-7 98%
Amtolmetin guacil (ST-679) inhibits prostaglandin synthesis and cyclooxygenase. Amtolmetin guacil has similar NSAID properties like tolmetin with additional anal...
T22346 Indomethacin sodium hydrate 74252-25-8 98%
Indomethacin Sodium is the sodium salt of indomethacin, which is a non-selective, competitive, and reversible, inhibitor of cyclooxygenases 1 and 2 with analgesi...
T6424 Bromfenac Sodium 91714-93-1
Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inh...
T0839L S-(+)-Ketoprofen 22161-81-5
S-(+)-Ketoprofen ((S)-(+)-Ketoprofen) works by blocking the action of a substance in the body called cyclo-oxygenase. It belongs to a class of medicines called n...
Amfenac Sodium Hydrate
T1720
Amfenac Sodium Hydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety.
Tarlox-TKI
T11761
Kinase inhibitor-1 is a kinase inhibitor.
Coniferaldehyde
TN3694
Coniferaldehyde can significantly inhibit the growth of viability of strains of Oenococcus oeni. Coniferaldehyde exerts anti-inflammatory properties by inducing ...
Crocin II
T3779
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect ...
(-)-Pinoresinol
TN2079
(-)-Pinoresinol is isolated from the whole plant of Serissa japonica (Thunb.) Thunb.
Benoxaprofen
T19679
Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.
Feladilimab
T77433
Feladilimab (GSK3359609) is an IgG4 monoclonal antibody that is an ICOS agonist. Feladilimab binds to ICOS-expressing T cells, induces IFNγ, and increases PD-1/L...
Metamizole sodium
T1191L
Metamizole sodium (Analgin) is a drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE.
Hamaline
T60053
Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) is a substrate-selective cyclooxygenase-2 (COX-2) inhibitor.
Sifalimumab
T76760
Sifalimumab (MEDI-545) is a monoclonal antibody that targets IFNα and suppresses abnormal immune activity by binding to interferon-alpha.Sifalimumab is used for ...
Emapalumab
T76742
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface rec...
Serplulimab
T76717
Serplulimab (HLX 10) is a humanized monoclonal anti-antibody to PD-1. Serplulimab has antitumor activity and can be used in small cell lung cancer and esophageal...
6-Hydroxyflavanone
TN1308
6-Hydroxyflavanone, extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxygenase-2 (COX...
1-O-Acetyl britannilactone
TN1143
1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR...
Compound Lup-20(29)-en-3-yl acetate
TC0036
Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.
Moringin
TN4583
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moring...
Amtolmetin guacil
T19672
Amtolmetin guacil (ST-679) inhibits prostaglandin synthesis and cyclooxygenase. Amtolmetin guacil has similar NSAID properties like tolmetin with additional anal...
Indomethacin sodium hydrate
T22346
Indomethacin Sodium is the sodium salt of indomethacin, which is a non-selective, competitive, and reversible, inhibitor of cyclooxygenases 1 and 2 with analgesi...
Bromfenac Sodium
T6424
Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inh...
S-(+)-Ketoprofen
T0839L
S-(+)-Ketoprofen ((S)-(+)-Ketoprofen) works by blocking the action of a substance in the body called cyclo-oxygenase. It belongs to a class of medicines called n...
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