ホーム 計算ツール
代理店ログイン

Carbonic Anhydrase

The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonic anhydrases contains a zinc ion. They are therefore classified as metalloenzymes. The enzyme maintains acid-base balance and helps transport carbon dioxide.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T1449 Hydrochlorothiazide 58-93-5 98%
Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.
T76684 Girentuximab 916138-87-9 98%
Girentuximab (G250) is a potent anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anticancer activity for the study of uroepithelial carcinoma PET (ZiPU...
T60351 Acetazolamide sodium 1424-27-7 98%
Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA)IX inhibitor with diuretic, antigonococcal, and antihypertensive activity and may be used...
T60745 HCAIX-IN-5 2451479-57-3 98%
hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.
T8611 2,3-dihydro-1H-indene-5-sulfonamide 35203-93-1 98%
2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.
T1026 Mafenide hydrochloride 138-37-4
Mafenide hydrochloride (4-Aminomethylbenzenesulfonamide hydrochloride) is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-i...
T2017 U-104 178606-66-1
U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).
T0515 Tioxolone 4991-65-5
Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.
T6781 Benzenesulfonamide 98-10-2
Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.
T67775 Enpp/Carbonic anhydrase-IN-1 2883495-35-8 100%
Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase. Enpp/Carbonic anhydrase-IN-1 exhibits IC50s of 1.36, 1.35, 3.00,...
T0142 Brinzolamide 138890-62-7 100%
Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.
T6581 Methyclothiazide 135-07-9 95.00%
Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including hea...
T5012 Ethoxzolamide 452-35-7 96.33%
Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.
T80663 HCAI/II/IV-IN-28 78659-11-7 96.48%
hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.
T6469 Dichlorphenamide 120-97-8 96.87%
Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
T23782 Benzolamide 3368-13-6 97.03%
Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.
T61745 HCAI/II-IN-6 694466-00-7 97.07%
hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA). hCAI/II-IN-6 inhibited hCA I, hCA II, hCA VII, and hCA XII with Ki valu...
T0738 Urea 57-13-6 98%
Urea (Carbonyldiamide) is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism a...
T0675 Topiramate 97240-79-4 98%
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
T4S2354 Dimethylfraxetin 6035-49-0 98%
Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)
Hydrochlorothiazide
T1449
Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.
Girentuximab
T76684
Girentuximab (G250) is a potent anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anticancer activity for the study of uroepithelial carcinoma PET (ZiPU...
Acetazolamide sodium
T60351
Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA)IX inhibitor with diuretic, antigonococcal, and antihypertensive activity and may be used...
hCAIX-IN-5
T60745
hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.
2,3-dihydro-1H-indene-5-sulfonamide
T8611
2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.
Mafenide hydrochloride
T1026
Mafenide hydrochloride (4-Aminomethylbenzenesulfonamide hydrochloride) is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-i...
U-104
T2017
U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).
Tioxolone
T0515
Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.
Benzenesulfonamide
T6781
Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.
Enpp/Carbonic anhydrase-IN-1
T67775
Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase. Enpp/Carbonic anhydrase-IN-1 exhibits IC50s of 1.36, 1.35, 3.00,...
Brinzolamide
T0142
Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.
Methyclothiazide
T6581
Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including hea...
Ethoxzolamide
T5012
Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.
hCAI/II/IV-IN-28
T80663
hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.
Dichlorphenamide
T6469
Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Benzolamide
T23782
Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.
hCAI/II-IN-6
T61745
hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA). hCAI/II-IN-6 inhibited hCA I, hCA II, hCA VII, and hCA XII with Ki valu...
Urea
T0738
Urea (Carbonyldiamide) is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism a...
Topiramate
T0675
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
Dimethylfraxetin
T4S2354
Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)
1 2 3 4