ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T17250 | W-54011 | 405098-33-1 | 98% |
|
| W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a... | ||||
| T38332 | Complement factor D-IN-2 | 1903742-34-6 | 98% |
|
| Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and... | ||||
| T8223 | Avacopan | 1346623-17-3 | 98% |
|
| Avacopan is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by a... | ||||
| TP2180L | Compstatin control peptide acetate | 301544-78-5 | 98% |
|
| Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3. | ||||
| T7497L | C3a 70-77 2TFA(63555-63-5(free base)) | T7497L | 98% |
|
| C3a 70-77 2TFA is an octapeptide corresponding to the COOH terminus of C3a. | ||||
| T9915 | Eculizumab | 219685-50-4 | 98% |
|
| Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5 | ||||
| TP1304 | Compstatin | 206645-99-0 | 98% |
|
| Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor. | ||||
| T7776 | ADH-503 | 2055362-74-6 | 98% |
|
| ADH-503 is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression. | ||||
| T38287 | C3a Receptor Agonist | 944997-60-8 | 98% |
|
| C3a Receptor Agonist binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from bein... | ||||
| T0945 | Cyclosporin A | 59865-13-3 | 98% |
|
| Cyclosporine A is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of cyclosporine is as a Calcineurin Inhibitor, and Cytochrome P450 3A4 Inhib... | ||||
| T3638 | Leukadherin-1 | 344897-95-6 | 98% |
|
| Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendot... | ||||
| T64388 | 3-Phenoxybenzaldehyde | 39515-51-0 | 98% |
|
| 3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM. | ||||
| T9189 | Iptacopan hydrochloride | 1646321-63-2 | 98% |
|
| LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. LNP023 shows direct, reversible, and... | ||||
| T12851 | SB290157 trifluoroacetate | 1140525-25-2 | 98% |
|
| SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM). | ||||
| T9316 | JR14a | 2411440-41-8 | 98% |
|
| JR14a is a potent antagonist of human complement C3a receptor. | ||||
| T12506L1 | PMX 205 acetate(514814-49-4 free base) | T12506L1 | 98% |
|
| PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88). | ||||
| T60151 | CP-447697 | 1092847-21-6 | 98% |
|
| CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation. | ||||
| T1076 | Dexamethasone | 50-02-2 | 98% |
|
| Dexamethasone is a glucocorticoid receptor agonist and an IL receptor modulator.Dexamethasone inhibits production of exosomes containing inflammatory microRNA-15... | ||||
| T60161 | CP-289 | 1349637-14-4 | 98% |
|
| CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM. | ||||
| T8509 | Danicopan | 1903768-17-1 | 98% |
|
| Danicopan (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Da... | ||||
