ホーム 計算ツール
代理店ログイン

DNA/RNA Synthesis

RNA synthesis, which is also called DNA transcription, is a highly selective process. Transcription by RNA polymerase II extends beyond RNA synthesis, towards a more active role in mRNA maturation, surveillance and export to the cytoplasm. Single-strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template, with DNA ligase creating the final phosphodiester bond to fully repair the DNA.DNA ligases discriminate against substrates containing RNA strands or mismatched base pairs at positions near the ends of the nickedDNA. Bleomycin (BLM) exerts its genotoxicity by generating free radicals, whichattack C-4′ in the deoxyribose backbone of DNA, leading to opening of the ribose ring and strand breakage; it is an S-independentradiomimetic agent that causes double-strand breaks in DNA.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T4470 Pyridostatin TFA 1472611-44-1 98%
Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-ki...
T37101 1-Hydroxyanthraquinone 129-43-1 98%
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone gener...
T23974 DDRI-18 4402-18-0 98%
DDRI-18 is a novel small molecule inhibitor that regulates the DNA damage response with sensitizing and anticancer activities, inhibits non-homologous end-joinin...
T36756 DMT-dG(ib) Phosphoramidite 93183-15-4 98%
DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.
T13584 BMVC-8C3O 1301708-12-2 98%
BMVC-8C3O, a DNA G-quadruplex (G4) ligand, induces the topological conversion from non-parallel to parallel forms in human telomeric DNA G4s.
TNU0442 2’-beta-C-Methyl inosine 374750-32-0 98%
2'-beta-C-Methyl inosine (2'-C-Methylinosine) is an HCV RNA polymerase inhibitor with antiviral activity that has been investigated for the treatment of Hepatiti...
T14522 Beaucage reagent 66304-01-6 98%
Beaucage reagent, which is found to be effective in causing DNA cleavage.
T6974 Saccharin 1-methylimidazole 482333-74-4 98%
Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.
T37635 2'-Deoxyadenosine-5'-triphosphate trisodium 54680-12-5 98%
2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide that serves as a substrate for DNA polymerase, which is used in cells for DNA synthe...
T6960L PU-H71 HCl 2095432-24-7 98%
PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL sho...
T77632 Antiviral agent 34 945152-88-5 98%
Antiviral agent 34 is an orally available, potent antiviral compound that inhibits influenza A and B viruses.Antiviral agent 34 inhibits the proliferation of inf...
T20038 2-Fluoroadenine 700-49-2 98%
2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.
T1378 Tegafur 17902-23-7 98%
Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil ...
T60028 MM41 1429028-96-5 98%
MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line.
T63253 AVG-233 2151937-80-1 98%
AVG-233 is an orally available RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity that blocks respiratory syncytial virus and SARS-CoV-2 repli...
T21498 Phleomycin 11006-33-0 98%
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the ...
T40179 Sodium Camptothecin 25387-67-1 98%
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effectiv...
T13592 Calf thymus DNA 91080-16-9 98%
Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) is a high-quality double-stranded template DNA extracted from the bovine thymus gland, which can be wid...
T12006 Metarrestin 1443414-10-5 98%
Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis. Metarrestin dis...
T2628 RI-2 1417162-36-7 98%
RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 μM in the standard DNA binding assay; specifically inhibits HR(Homologous recombination) repair in hum...
Pyridostatin TFA
T4470
Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-ki...
1-Hydroxyanthraquinone
T37101
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone gener...
DDRI-18
T23974
DDRI-18 is a novel small molecule inhibitor that regulates the DNA damage response with sensitizing and anticancer activities, inhibits non-homologous end-joinin...
DMT-dG(ib) Phosphoramidite
T36756
DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.
BMVC-8C3O
T13584
BMVC-8C3O, a DNA G-quadruplex (G4) ligand, induces the topological conversion from non-parallel to parallel forms in human telomeric DNA G4s.
2’-beta-C-Methyl inosine
TNU0442
2'-beta-C-Methyl inosine (2'-C-Methylinosine) is an HCV RNA polymerase inhibitor with antiviral activity that has been investigated for the treatment of Hepatiti...
Beaucage reagent
T14522
Beaucage reagent, which is found to be effective in causing DNA cleavage.
Saccharin 1-methylimidazole
T6974
Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.
2'-Deoxyadenosine-5'-triphosphate trisodium
T37635
2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide that serves as a substrate for DNA polymerase, which is used in cells for DNA synthe...
PU-H71 HCl
T6960L
PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL sho...
Antiviral agent 34
T77632
Antiviral agent 34 is an orally available, potent antiviral compound that inhibits influenza A and B viruses.Antiviral agent 34 inhibits the proliferation of inf...
2-Fluoroadenine
T20038
2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.
Tegafur
T1378
Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil ...
MM41
T60028
MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line.
AVG-233
T63253
AVG-233 is an orally available RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity that blocks respiratory syncytial virus and SARS-CoV-2 repli...
Phleomycin
T21498
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the ...
Sodium Camptothecin
T40179
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effectiv...
Calf thymus DNA
T13592
Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) is a high-quality double-stranded template DNA extracted from the bovine thymus gland, which can be wid...
Metarrestin
T12006
Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis. Metarrestin dis...
RI-2
T2628
RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 μM in the standard DNA binding assay; specifically inhibits HR(Homologous recombination) repair in hum...
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18