ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T6712 | Tyrphostin AG 879 | 148741-30-4 | 98% |
|
| Tyrphostin AG 879 effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR. | ||||
| T11161 | EGFR-IN-7 | 2267329-76-8 | 98% |
|
| EGFR-IN-7 is a selective and potent EGFR kinase inhibitor. | ||||
| T14138 | AG-825 | 149092-50-2 | 98% |
|
| AG-825（Tyrphostin C15） is a selective and competitive ErbB2 inhibitor that inhibits tyrosine phosphorylation with an IC50 value of 0.35 μM.AG-825 (Tyrphostin C15... | ||||
| T1761 | PD153035 hydrochloride | 183322-45-4 | 98% |
|
| PD153035 hydrochloride (ZM 252868; AG 1517) is a effective and selective inhibitor of EGFR (Ki: 5.2 pM, IC50: 29 pM); few influence against FGFR, PGDFR, InsR, CS... | ||||
| T39595 | Disitamab vedotin | 2136633-23-1 | 98% |
|
| Disitamab vedotin is an antibo-active molecular conjugate (ADC) containing a monoclonal antibody against human epidermal growth factor receptor 2 (HER2) that bin... | ||||
| T0078L | Lapatinib ditosylate | 388082-78-8 | 98% |
|
| Lapatinib is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumors. Lapatinib therapy is associated with tran... | ||||
| T67385 | Neratinib maleate | 915942-22-2 | 98% |
|
| Neratinib maleate is an irreversible, orally active and highly selective inhibitor of HER2 and EGFR with IC50 values of 59 nM and 92 nM, respectively.Neratinib m... | ||||
| T9905 | Cetuximab | 205923-56-4 | 98% |
|
| Cetuximab (anti-EGFR) a novel molecular-targeted agentis an inhibitor of EGFR monoclonal humanized antibody interacting with the extracellular binding site of EG... | ||||
| T2041 | PD153035 | 153436-54-5 | 98% |
|
| PD153035 hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR, PGDFR, InsR, CS... | ||||
| T12594 | Pyrotinib dimaleate | 1397922-61-0 | 98% |
|
| Pyrotinib dimaleate is a potent and selective dual inhibitor of EGFR/HER2 (IC50 s of 13 and 38 nM, respectively). | ||||
| T60064 | WAY-270360 | 476633-98-4 | 98% |
|
| WAY-270360 is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor. | ||||
| T1431 | Khellin | 82-02-0 | 98% |
|
| Khellin is a vasodilator that also has bronchodilatory action. | ||||
| T60076 | Oritinib | 2035089-28-0 | 98% |
|
| Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), E... | ||||
| T21853 | (E)-AG 556 | 133550-41-1 | 98% |
|
| AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production. | ||||
| T2491 | AZ-5104 | 1421373-98-9 | 98% |
|
| AZ5104 is a potent EGFR inhibitor. | ||||
| T61191 | EAI001 | 892772-75-7 | 98% |
|
| EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.EAI00... | ||||
| T2032 | WHI-P180 | 211555-08-7 | 98% |
|
| WHI-P180 is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively. | ||||
| T3659 | Zorifertinib | 1626387-80-1 | 98% |
|
| AZD3759 is an orally active, effective and central nervous system-penetrant EGFR inhibitor. The IC50 values were 0.2, 0.3 and 0.2 nM for EGFR L858R mutant, TK wi... | ||||
| T9909 | Pertuzumab | 380610-27-5 | 98% |
|
| Pertuzumab anti-HER2) a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2 to... | ||||
| T6008 | CNX-2006 | 1375465-09-0 | 98% |
|
| CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR. | ||||
