GPX

Glutathione peroxidase (GPx) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage. The biochemical function of glutathione peroxidase is to reduce lipid hydroperoxides to their corresponding alcohols and to reduce free hydrogen peroxide to water.

Cat. No.	製品名	CAS No.	Purity
T37314	JKE-1674	2421119-60-8	98%
T37314	JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4) and an active metabolite of the GPX4 inhibitor ML-210 .1JKE-1674 reduces viability of LOX-IMVI cancer...
T19117	3-Deoxyglucosone	4084-27-9	98%
T19117	3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein a...
T36935	PKUMDL-LC-101-D04	2143896-83-5	98%
T36935	PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of iron death. GPX4 activity was increased to 150% of control ...
T21899	Misonidazole	13551-87-6	98%
T21899	Misonidazole as a novel GPX inhibitors to cause oxidative stress in chemotherapy-resistant tumors.
T8375	ML-210	1360705-96-9	98%
T8375	ML-210 is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
T8970	ML162	1035072-16-2	98%
T8970	ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-typ...
T3646	RSL3	1219810-16-8	98%
T3646	RSL3 is a VDAC-independent ferroptosis activator with selectivity for tumor cells bearing oncogenic RAS. RSL3 is the inhibitor of the glutathione peroxidase 4, w...