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HIV Protease

HIV-1 protease (PR) is a retroviral aspartyl protease (retropepsin), an enzyme involved with peptide bond hydrolysis in retroviruses, that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV protease cleaves newly synthesized polyproteins (namely, Gag and Gag-Pol[3]) at nine cleavage sites to create the mature protein components of an HIV virion, the infectious form of a virus outside of the host cell. Without effective HIV protease, HIV virions remain uninfectious.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T4665 Temsavir 701213-36-7 98%
BMS-626529 is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
T2324 Darunavir 206361-99-1 98%
Darunavir is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alon...
T3335 Darunavir Ethanolate 635728-49-3 98%
Darunavir ethanolate is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE whe...
T3465 Vesnarinone 81840-15-5 98%
Vesnarinone (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal neg...
T0753 Salicylanilide 87-17-2 98%
Salicylanilides are a group of compounds with antiviral potency, antibacterial and antifungal activities.
T7212 Delavirdine mesylate 147221-93-0 98%
Delavirdine (mesylate) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
T15210 Elsulfavirine 868046-19-9 98%
Elsulfavirine is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.
T6653 Salmeterol Xinafoate 94749-08-3 98%
Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstruc...
T0457 Probenecid 57-66-9 98%
Probenecid is a benzoic acid derivative with antihyperuricemic property.
T2393 Efavirenz 154598-52-4 98%
Efavirenz is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of efavirenz is as a Non-Nucleoside ...
T2239 Raltegravir potassium 871038-72-1 98%
Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
T1776L Plerixafor octahydrochloride 155148-31-5 98%
AMD 3100 octahydrochloride blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (H...
TN1660 Ganoderic acid C1 95311-97-0 98%
Ganoderic acid C1 has anti-inflammatory activity, has potential for treating TNF-α± mediated inflammation in asthma and other inflammatory diseases. Ganoderic ac...
T0070 Pentoxifylline 6493-05-6 98%
Pentoxifylline modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase a...
T7282 Tenofovir alafenamide hemifumarate 1392275-56-7 98%
Tenofovir alafenamide fumarate (TAF) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV)
T4557 Amylmetacresol 1300-94-3 98%
Amylmetacresol is used in the treatment of sore throat or 'acute sore throat', pharyngitis, tonsillitis and laryngitis. As well as in the treatment of influenza ...
T25913L P-113 acetate 98%
P-113 acetate is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5, shows good safety and efficacy profiles in gingivitis and hum...
TN1622 Ermanin 20869-95-8 98%
Ermanin is a flavonoid isolated from Tanacetum microphyllum.Ermanin inhibits platelet aggregation and has anti-tuberculosis and anti-viral/bacterial properties.E...
T5863 Indinavir sulfate 157810-81-6 98%
Indinavir is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.
T6841 Fumagillin 23110-15-8 98%
Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
Temsavir
T4665
BMS-626529 is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
Darunavir
T2324
Darunavir is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alon...
Darunavir Ethanolate
T3335
Darunavir ethanolate is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE whe...
Vesnarinone
T3465
Vesnarinone (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal neg...
Salicylanilide
T0753
Salicylanilides are a group of compounds with antiviral potency, antibacterial and antifungal activities.
Delavirdine mesylate
T7212
Delavirdine (mesylate) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
Elsulfavirine
T15210
Elsulfavirine is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.
Salmeterol Xinafoate
T6653
Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstruc...
Probenecid
T0457
Probenecid is a benzoic acid derivative with antihyperuricemic property.
Efavirenz
T2393
Efavirenz is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of efavirenz is as a Non-Nucleoside ...
Raltegravir potassium
T2239
Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
Plerixafor octahydrochloride
T1776L
AMD 3100 octahydrochloride blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (H...
Ganoderic acid C1
TN1660
Ganoderic acid C1 has anti-inflammatory activity, has potential for treating TNF-α± mediated inflammation in asthma and other inflammatory diseases. Ganoderic ac...
Pentoxifylline
T0070
Pentoxifylline modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase a...
Tenofovir alafenamide hemifumarate
T7282
Tenofovir alafenamide fumarate (TAF) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV)
Amylmetacresol
T4557
Amylmetacresol is used in the treatment of sore throat or 'acute sore throat', pharyngitis, tonsillitis and laryngitis. As well as in the treatment of influenza ...
P-113 acetate
T25913L
P-113 acetate is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5, shows good safety and efficacy profiles in gingivitis and hum...
Ermanin
TN1622
Ermanin is a flavonoid isolated from Tanacetum microphyllum.Ermanin inhibits platelet aggregation and has anti-tuberculosis and anti-viral/bacterial properties.E...
Indinavir sulfate
T5863
Indinavir is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.
Fumagillin
T6841
Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
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