ROS

Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen. Examples include peroxides, superoxide, hydroxyl radical, singlet oxygen, and alpha-oxygen. The reduction of molecular oxygen (O2) produces superoxide (•O−2), which is the precursor of most other reactive oxygen species.In a biological context, ROS are formed as a natural byproduct of the normal metabolism of oxygen and have important roles in cell signaling and homeostasis. However, during times of environmental stress (e.g., UV or heat exposure), ROS levels can increase dramatically.

Cat. No.	製品名	CAS No.	Purity
TN4675	Nortrachelogenin	34444-37-6	98%
TN4675	Nortrachelogenin ((-)-Wikstromol), which can be extracted from Partrinia scabiosaefolia, has antifungal activity and induces membrane disruption and cysteinyl as...
T17250	W-54011	405098-33-1	98%
T17250	W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a...
T6376	Allopurinol Sodium	17795-21-0	98%
T6376	Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
TN3967	Epieriocalyxin A	191545-24-1	98%
TN3967	Epieriocalyxin A can suppress Caco-2 colon cancer cell growth, it could be a potential drug for colon cancer therapy in the future.
T77579	JC2-11	937820-89-8	98%
T77579	JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical ...
T77578	CHBO4	98991-32-3	98%
T77578	CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the...
T2858	Baicalein	491-67-8	98%
T2858	Baicalein is a xanthine oxidase inhibitor.
T5518	N-acetylcysteine amide	38520-57-9	98%
T5518	N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective agent
TN3601	Carminic acid	1260-17-9	98%
TN3601	Carminic acid, the well-known red dyestuff from cochineal insects (Dactylopius spp.), is a potent feeding deterrent to ants. Carminic acid is an antioxidant to p...
T72072	2-benzylsulfanyl-6-methoxy-4-methylquinazoline	500272-00-4	98%
T72072	2-benzylsulfanyl-6-methoxy-4-methylquinazoline can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity, such as lysosomal s...
TN1067	Galloylpaeoniflorin	122965-41-7	98%
TN1067	6'-O-Galloylpaeoniflorin (GPF) may be developed as a cytoprotector against ROS-mediated oxidative stress
TN1624	Ethyl cinnamate	103-36-6	98%
TN1624	Ethyl cinnamate has antifungal, and vasorelaxant effects, it can inhibit the tonic contractions induced by high K+ and phenylephrine (PE) in a concentration-depe...
TN1425	Bacoside A3	157408-08-7	98%
TN1425	Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.
T6699	Tempol	2226-96-2	98%
T6699	Tempol is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.
T3061	Lorlatinib	1454846-35-5	98%
T3061	PF-06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), wit...
T36488	LYG-202	1175077-25-4	98%
T36488	LYG-202 is a novel flavonoid with piperazine substitution and antitumor effects in vivo and in vitro.LYG-202 induced apoptosis in MCF-7, MDA-MB-231, and MDA-MB-4...
T0773	Febuxostat	144060-53-7	98%
T0773	Febuxostat is a xanthine oxidase Inhibitor.
TN1918	Medicarpin	32383-76-9	98%
TN1918	Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERα², promote achievement of pea...
T6S1255	Ophiopogonin-D	41753-55-3	98%
T6S1255	Ophiopogonin D(OPD) significantly inhibited the in vitro and in vivo growth of prostate cells via RIPK1, OPD may be developed as a potential anti-prostate cancer...
TJS1779	Protosappanin A	102036-28-2	98%
TJS1779	Protosappanin A has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IÎºB/NF-ÎºB inflammat...