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Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T2806 Lappaconitine 32854-75-4 98%
Lappaconitine, isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.
T31716 Etidocaine Hydrochloride 36637-19-1 98%
Etidocaine Hydrochloride (Duranest, W-19053) is a voltage-gated sodium channel blocker used as an anesthetic with extended action.
T27205 DPI 201-106 97730-95-5 98%
DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delay...
T1144 Lidocaine hydrochloride 73-78-9 98%
Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmic agent. Its actions are more intense and its effects more prolonged...
T0440 Oxcarbazepine 28721-07-5 98%
Oxcarbazepine is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activit...
T9685 DS-1971a 1450595-86-4 98%
DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.
T6782L Benzocaine xHCl(94-09-7(free base)) T6782L 98%
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).
T1320 Disopyramide 3737-09-5 98%
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) wi...
T69552 Suzetrigine 2649467-58-1 98%
Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmissi...
T0806 Flunarizine dihydrochloride 30484-77-6 98%
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine hydrochloride is effective in...
T6566 Levobupivacaine hydrochloride 27262-48-2 98%
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local a...
T34081 Piromelatine 946846-83-9 98%
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibito...
T37688 Cyfluthrin 68359-37-5 98%
Cyfluthrin is a pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).1,2It slowly activates rat recombinant Nav1.8 channels, delays inac...
T1389 Dyclonine hydrochloride 536-43-6 98%
Dyclonine, an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .
T19554 L-Aspartic aicd sodium 3792-50-5 98%
L-Aspartic aicd sodium is an amino acid, a precursor active molecule for colon-specific active molecule delivery, that promotes Na+ efflux from rat forebrain mem...
T0916 Butamben 94-25-7 98%
Butamben is a long-duration local anesthetic used for the treatment of chronic pain.
T1332 Permethrin 52645-53-1 98%
Permethrin is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.
T6541 Ibutilide Fumarate 122647-32-9 98%
Ibutilide Fumarate is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominat...
T0030 Bupivacaine hydrochloride 18010-40-7 98%
Bupivacaine Hydrochloride is a long-acting, amide-type local anesthetic. Bupivacaine reversibly binds to specific sodium ion channels in the neuronal membrane, r...
T6645 Ropivacaine hydrochloride monohydrate 132112-35-7 98%
Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
Lappaconitine
T2806
Lappaconitine, isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.
Etidocaine Hydrochloride
T31716
Etidocaine Hydrochloride (Duranest, W-19053) is a voltage-gated sodium channel blocker used as an anesthetic with extended action.
DPI 201-106
T27205
DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delay...
Lidocaine hydrochloride
T1144
Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmic agent. Its actions are more intense and its effects more prolonged...
Oxcarbazepine
T0440
Oxcarbazepine is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activit...
DS-1971a
T9685
DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.
Benzocaine xHCl(94-09-7(free base))
T6782L
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).
Disopyramide
T1320
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) wi...
Suzetrigine
T69552
Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmissi...
Flunarizine dihydrochloride
T0806
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine hydrochloride is effective in...
Levobupivacaine hydrochloride
T6566
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local a...
Piromelatine
T34081
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibito...
Cyfluthrin
T37688
Cyfluthrin is a pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).1,2It slowly activates rat recombinant Nav1.8 channels, delays inac...
Dyclonine hydrochloride
T1389
Dyclonine, an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .
L-Aspartic aicd sodium
T19554
L-Aspartic aicd sodium is an amino acid, a precursor active molecule for colon-specific active molecule delivery, that promotes Na+ efflux from rat forebrain mem...
Butamben
T0916
Butamben is a long-duration local anesthetic used for the treatment of chronic pain.
Permethrin
T1332
Permethrin is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.
Ibutilide Fumarate
T6541
Ibutilide Fumarate is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominat...
Bupivacaine hydrochloride
T0030
Bupivacaine Hydrochloride is a long-acting, amide-type local anesthetic. Bupivacaine reversibly binds to specific sodium ion channels in the neuronal membrane, r...
Ropivacaine hydrochloride monohydrate
T6645
Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
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