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Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T27205 DPI 201-106 97730-95-5 98%
DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delay...
T69552 Suzetrigine 2649467-58-1 98%
Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmissi...
T37688 Cyfluthrin 68359-37-5 98%
Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests....
T6086 Clopamide 636-54-4 98%
Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.
T0275 Meticrane 1084-65-7 98%
Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.
T7547 Ralfinamide mesylate 202825-45-4 98%
Ralfinamide mesylate (FCE-26742A (mesylate)) is an orally available Na+ channel blocker.
TN1254 3'-Methoxydaidzein 21913-98-4 98%
3'-Methoxydaidzein is a dual isoflavone and Sodium Channel inhibitor. 3'-Methoxydaidzein inhibited NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM and 505 ...
T7502 PF 05089771 tosylate 1430806-04-4 98%
PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50: 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respec...
TQ0157 EIPA 1154-25-2 98%
EIPA (L593754) (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
T31716 Etidocaine Hydrochloride 36637-19-1
Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel.
T9685 DS-1971a 1450595-86-4
DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.
T6782L Benzocaine xHCl(94-09-7(free base)) T6782L
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).
T0175 Amiloride hydrochloride 2016-88-8
Amiloride hydrochloride (Amiloride HCl) is an effective sodium channel blocker of epithelial.
T1332 Permethrin 52645-53-1
Permethrin (NRDC-143) is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.
T0511 Tolperisone hydrochloride 3644-61-9
Tolperisone hydrochloride (Muscalm), a centrally acting muscle relaxant, is used in the therapy of pathologically increased tone of the cross-striated muscle res...
T21769L β-Pompilidotoxin Acetate T21769L
β-Pompilidotoxin Acetate is a wasp venom peptide. β-Pompilidotoxin Acetate can slow sodium channel inactivation and increase steady-state sodium current in cells...
T0029 Procaine 59-46-1
Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia...
T9234 Tocainide hydrochloride 35891-93-1
Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker. It blocks the sodium channels in the pain-producin...
T3285L Eslicarbazepine 104746-04-5
Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.
T1320 Disopyramide 3737-09-5 100%
Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a me...
DPI 201-106
T27205
DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delay...
Suzetrigine
T69552
Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmissi...
Cyfluthrin
T37688
Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests....
Clopamide
T6086
Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.
Meticrane
T0275
Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.
Ralfinamide mesylate
T7547
Ralfinamide mesylate (FCE-26742A (mesylate)) is an orally available Na+ channel blocker.
3'-Methoxydaidzein
TN1254
3'-Methoxydaidzein is a dual isoflavone and Sodium Channel inhibitor. 3'-Methoxydaidzein inhibited NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM and 505 ...
PF 05089771 tosylate
T7502
PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50: 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respec...
EIPA
TQ0157
EIPA (L593754) (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
Etidocaine Hydrochloride
T31716
Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel.
DS-1971a
T9685
DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.
Benzocaine xHCl(94-09-7(free base))
T6782L
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).
Amiloride hydrochloride
T0175
Amiloride hydrochloride (Amiloride HCl) is an effective sodium channel blocker of epithelial.
Permethrin
T1332
Permethrin (NRDC-143) is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.
Tolperisone hydrochloride
T0511
Tolperisone hydrochloride (Muscalm), a centrally acting muscle relaxant, is used in the therapy of pathologically increased tone of the cross-striated muscle res...
β-Pompilidotoxin Acetate
T21769L
β-Pompilidotoxin Acetate is a wasp venom peptide. β-Pompilidotoxin Acetate can slow sodium channel inactivation and increase steady-state sodium current in cells...
Procaine
T0029
Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia...
Tocainide hydrochloride
T9234
Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker. It blocks the sodium channels in the pain-producin...
Eslicarbazepine
T3285L
Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.
Disopyramide
T1320
Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a me...
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