T2806 |
Lappaconitine
|
32854-75-4
|
98%
|
|
Lappaconitine, isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.
|
T31716 |
Etidocaine Hydrochloride
|
36637-19-1
|
98%
|
|
Etidocaine Hydrochloride (Duranest, W-19053) is a voltage-gated sodium channel blocker used as an anesthetic with extended action.
|
T27205 |
DPI 201-106
|
97730-95-5
|
98%
|
|
DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delay...
|
T1144 |
Lidocaine hydrochloride
|
73-78-9
|
98%
|
|
Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmic agent. Its actions are more intense and its effects more prolonged...
|
T0440 |
Oxcarbazepine
|
28721-07-5
|
98%
|
|
Oxcarbazepine is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activit...
|
T9685 |
DS-1971a
|
1450595-86-4
|
98%
|
|
DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.
|
T6782L |
Benzocaine xHCl(94-09-7(free base))
|
T6782L
|
98%
|
|
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).
|
T1320 |
Disopyramide
|
3737-09-5
|
98%
|
|
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) wi...
|
T69552 |
Suzetrigine
|
2649467-58-1
|
98%
|
|
Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmissi...
|
T0806 |
Flunarizine dihydrochloride
|
30484-77-6
|
98%
|
|
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine hydrochloride is effective in...
|
T6566 |
Levobupivacaine hydrochloride
|
27262-48-2
|
98%
|
|
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local a...
|
T34081 |
Piromelatine
|
946846-83-9
|
98%
|
|
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibito...
|
T37688 |
Cyfluthrin
|
68359-37-5
|
98%
|
|
Cyfluthrin is a pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).1,2It slowly activates rat recombinant Nav1.8 channels, delays inac...
|
T1389 |
Dyclonine hydrochloride
|
536-43-6
|
98%
|
|
Dyclonine, an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .
|
T19554 |
L-Aspartic aicd sodium
|
3792-50-5
|
98%
|
|
L-Aspartic aicd sodium is an amino acid, a precursor active molecule for colon-specific active molecule delivery, that promotes Na+ efflux from rat forebrain mem...
|
T0916 |
Butamben
|
94-25-7
|
98%
|
|
Butamben is a long-duration local anesthetic used for the treatment of chronic pain.
|
T1332 |
Permethrin
|
52645-53-1
|
98%
|
|
Permethrin is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.
|
T6541 |
Ibutilide Fumarate
|
122647-32-9
|
98%
|
|
Ibutilide Fumarate is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominat...
|
T0030 |
Bupivacaine hydrochloride
|
18010-40-7
|
98%
|
|
Bupivacaine Hydrochloride is a long-acting, amide-type local anesthetic. Bupivacaine reversibly binds to specific sodium ion channels in the neuronal membrane, r...
|
T6645 |
Ropivacaine hydrochloride monohydrate
|
132112-35-7
|
98%
|
|
Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
|