ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| TQ0181 | Resatorvid | 243984-11-4 | 98% |
|
| Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 n... | ||||
| T39669 | TLR7/8/9-IN-1 | 2180127-82-4 | 98% |
|
| TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM. | ||||
| T19675 | SM360320 | 226907-52-4 | 98% |
|
| SM360320 is an effective and selective agonist of TLR7. SM360320 inhibits HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to it... | ||||
| T39654 | Afimetoran | 2171019-55-7 | 98% |
|
| Afimetoran is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases. | ||||
| T37292 | M62812 | 613263-00-6 | 98% |
|
| TLR4 inhibitor. Inhibits LPS-induced NF-κB activation in HEK293 cells (IC50 = 2.4 μg/mL). Also inhibits LPS-induced cytokine production and procoagulant effects ... | ||||
| TN1936 | Mogroside III-E | 88901-37-5 | 98% |
|
| Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, has anti-inflammatory activity, it attenuates LPS-induced acute lung injury in... | ||||
| T8689 | Chloroquine | 54-05-7 | 98% |
|
| Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and... | ||||
| T3795 | Corilagin | 23094-69-1 | 98% |
|
| Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the ... | ||||
| T77353 | MyD88-IN-1 | 2911609-80-6 | 98% |
|
| MyD88-IN-1 is a potent MyD88 inhibitor MyD88-IN-1 has anti-inflammatory activity and inhibits downstream inflammatory signaling pathways, including the NF-κB pat... | ||||
| T76089 | Pepinh-TRIF TFA | 98% |
|
|
| Pepinh-TRIF TFA is a 30 aa peptide associated with the immune system that blocks TRIF signaling by interfering with TLR-TRIF interaction (TLR-TRIF interaction ).... | ||||
| T72253 | AXC-715 trihydrochloride | 2479276-17-8 | 98% |
|
| AXC-715 trihydrochloride is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings. The couplings are mostly programmed death ligand 1... | ||||
| T15371 | Gardiquimod | 1020412-43-4 | 98% |
|
| Gardiquimod is a TLR7/8 agonist. When used at concentrations below 10 μM, Gardiquimod specifically activates TLR7. Gardiquimod could inhibit HIV-1 infection of m... | ||||
| T23171 | Polyinosinic-polycytidylic acid | 24939-03-5 | 98% |
|
| Poly (I:C) is a synthetic double-stranded RNA (dsRNA) analog and is an immunostimulant that acts as the most potent interferon (IFN) inducer. It also is a Toll-l... | ||||
| T9287 | Hydroxychloroquine | 118-42-3 | 98% |
|
| Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a med... | ||||
| T60052 | BMS-905 | 2205846-49-5 | 98% |
|
| BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 and other family members. BMS-905 can be used in studies about the treatm... | ||||
| T8503 | TLR4-IN-C34 | 40592-88-9 | 98% |
|
| TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis | ||||
| T11598 | IAXO-102 | 1115270-63-7 | 98% |
|
| IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling. It inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflam... | ||||
| T12516 | Polyinosinic-polycytidylic acid sodium | 42424-50-0 | 98% |
|
| Polyinosinic-polycytidylic acid sodium is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gen... | ||||
| TP1938L | RS09 2TFA (1449566-36-2 free base) | TP1938L | 98% |
|
| RS09 2TFA is a TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. It acts as an ad... | ||||
| T24178 | Isatoribine | 122970-40-5 | 98% |
|
| Isatoribine(ANA245) free base is a potent TLR7 receptor agonist with anti-hepatitis C virus infection activity for the study of HCV infection. | ||||
