keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membrane.
説明 | (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membrane. |
ターゲット&IC50 | PTH:69 nM(Ki) |
In vitro | In opossum kidney (OK) cells, (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate (0.05-10 μM) inhibits PTHrP or PTH-stimulated cAMP formation in causes a concentration-dependent manner. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate (0.1-10 μM) attenuates the inhibition of NapiT promoted by 1 nM of either PTHrP or PTH[1]. |
In vivo | In hypercalcemic athymic nude mice bearing a human squamous cell carcinoma of the lung, administration of (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate (1 mg/mL once, 0.1 mg/mL for 6 h; i.v.) has no significant effect on serum calcium levels[2]. |
分子量 | N/A |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50.00mg/ml
You can also refer to dose conversion for different animals. 詳細
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(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate Endocrinology/Hormones Thyroid hormone receptor(THR) (D Trp12,Tyr34) pTH (7 34) amide (bovine) acetate (D-Trp12,Tyr34)-pTH (D-Trp-12,Tyr34)-pTH (7-34) amide (bovine) acetate (DTrp12,Tyr34)pTH (734) amide (bovine) acetate (D-Trp12,Tyr34)-pTH amide Acetate Inhibitor inhibitor inhibit