Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2614W94 is a selective inhibitor of MAO-A with IC50 of 5 nM and Ki of 1.6 nM.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 58,000 |
5 mg | 在庫あり | ¥ 114,000 |
10 mg | 在庫あり | ¥ 166,000 |
25 mg | 在庫あり | ¥ 259,500 |
50 mg | 在庫あり | ¥ 349,000 |
100 mg | 在庫あり | ¥ 454,500 |
500 mg | 在庫あり | ¥ 911,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 128,500 |
説明 | 2614W94 is a selective inhibitor of MAO-A with IC50 of 5 nM and Ki of 1.6 nM. |
ターゲット&IC50 | MAO:(ki)1.6 nM , MAO:5 nM |
In vitro | 2614W94 (30 nM) shows no inhibition of MAO-B[1]. |
In vivo | In rats, 2614W94 (5 mg/kg, p.o.) selectively inhibits MAO-A in brains and livers and elevates neurotransmitter amines in brain, inparticular serotonin and norepinephrine, with a redcution of their oxidized metabolites. 2614W94 (0.5, 1, 2 mg/kg, p.o.) dose-dependently potentiates 5-hydroxytryptophan-induced head twitches with an extrapolated ED50 of 1.1 mg/kg[1]. |
分子量 | 344.31 |
分子式 | C15H11F3O4S |
CAS No. | 205187-35-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (130.7 mM)
You can also refer to dose conversion for different animals. 詳細
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2614W94 205187-35-5 Metabolism Neuroscience MAO 2614W-94 Inhibitor inhibitor inhibit