Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-Methoxytryptophol (2-(5-Methoxy-1H-indol-3-yl)ethanol) is a pineal indoleamine derived from serotonin shown to be biologically active in a number of species.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 7,000 | |||
25 mg | 在庫あり | ¥ 15,000 | |||
50 mg | 在庫あり | ¥ 22,500 | |||
100 mg | 在庫あり | ¥ 34,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 9,000 |
説明 | 5-Methoxytryptophol (2-(5-Methoxy-1H-indol-3-yl)ethanol) is a pineal indoleamine derived from serotonin shown to be biologically active in a number of species. |
In vitro | In MC3T3-E1 cells, most of the 5-methoxytryptophol doses reduced slightly the metabolic activity of osteoblasts. After 14 days of cell culture, Rankl mRNA levels were decreased. 5-methoxytryptophol also induced a high osteocalcin secretion and mineralization capacity. In RAW264.7 cells, 5-methoxytryptophol decreased the number of osteoclast formed and its activity. 5-methoxytryptophol promoted activation of the ERK1/2 pathway through the phosphorylation of ERK, while LUZ addition suppressed this effect. In conclusion, 5-methoxytryptophol inhibits osteoclastogenesis and promoting osteoblast differentiation[3]. |
別名 | 2-(5-Methoxy-1H-indol-3-yl)ethanol, Methoxytryptophol |
分子量 | 191.23 |
分子式 | C11H13NO2 |
CAS No. | 712-09-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 88 mg/mL (460.18 mM)
You can also refer to dose conversion for different animals. 詳細
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5-Methoxytryptophol 712-09-4 Metabolism Endogenous Metabolite 2-(5-Methoxy-1H-indol-3-yl)ethanol Inhibitor Methoxytryptophol 5 Methoxytryptophol 5Methoxytryptophol inhibit inhibitor